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Summary Expression Gene Literature (5) GO Terms (6) Nucleotides (791) Proteins (36) Interactants (419) Wiki
XB-GENEPAGE-947406
Gene Symbol:
tubb4a

Gene Name:
tubulin beta 4A class IVa

Synonyms:
tubulin beta4 ( Add synonyms , Nomenclature history )

Gene Function:
microtubule component

Protein Function :
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
hypomyelinating leukodystrophy 6 [+]

OMIM:
DYSTONIA 4, TORSION, AUTOSOMAL DOMINANT; DYT4 [+]

External Links:
 
Xenbase Gene ID XB-GENE-947407 XB-GENE-17331002 XB-GENE-947413
Gene Symbol tubb4a tubb4a.L tubb4a.S
Chromosome Chr3 chr3L Scaffold20
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394927
108711727
379359
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tubb4a tubb4a.L tubb4a.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards TUBB4A OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tubb4a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tubb4a Ensembl
zebrafish
chicken
fruit fly
Publications
First Expression of a novel N-CAM glycoform (NOC-1) on axon tracts in embryonic Xenopus brain., Dev Dyn 1996        
Most Recent Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasia., Genesis 2021            
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 0 term 6 terms 6 terms
PANTHER tubb4a
KEGG Pathways K07375 K07375
KOG [Z] Beta tubulin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tubb4a
ORFs tufm ORF1 tubb4a.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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