Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (4) GO Terms (8) Nucleotides (334) Proteins (47) Interactants (204) Wiki
XB-GENEPAGE-947461
Gene Symbol:
gamt

Gene Name:
guanidinoacetate N-methyltransferase

Synonyms:
gamt-b , gamt-a ( Add synonyms , Nomenclature history )

Gene Function:
Guanidinoacetate methyltransferase and related proteins

Protein Function :
Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
guanidinoacetate methyltransferase deficiency

OMIM:
CEREBRAL CREATINE DEFICIENCY SYNDROME 2; CCDS2

External Links:
1/5
 
Xenbase Gene ID XB-GENE-947462 XB-GENE-947468 XB-GENE-6256537
Gene Symbol gamt gamt.L gamt.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394491
733150
380384
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gamt gamt.L gamt.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards GAMT OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gamt MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gamt Ensembl
zebrafish
ZFIN, AGR gamt ZFIN Ensembl
chicken
GEISHA GAMT Ensembl
fruit fly
Publications
First Activation of GABA(A) receptors by guanidinoacetate: a novel pathophysiological mechanism., Neurobiol Dis 2002  
Most Recent γ-Aminobutyric acid transporter 2 mediates the hepatic uptake of guanidinoacetate, the creatine biosynthetic precursor, in rats., PLoS One 2012          
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 3 terms 3 terms
PANTHER gamt
KEGG Pathways K00542 K00542 K00542
KOG [E] Guanidinoacetate methyltransferase and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gamt
ORFs gamt ORF1 gamt.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info