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Summary Expression Gene Literature (153) GO Terms (29) Nucleotides (203) Proteins (58) Interactants (728) Wiki
XB-GENEPAGE-947773
Gene Symbol:
gnas

Gene Name:
GNAS complex locus

Synonyms:
galphas , g alpha s , gas ( Add synonyms , Nomenclature history )

Gene Function:
G protein subunit Galphas, small G protein superfamily

Protein Function :
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl ...[+]


InterPro :
Na/sul symport CS , SLC13A/DASS , Gprotein alpha S , GproteinA insert [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Albright's hereditary osteodystrophy [+]

OMIM:
PITUITARY ADENOMA 1, MULTIPLE TYPES; PITA1 [+]

External Links:
1/3
 
Xenbase Gene ID XB-GENE-947774 XB-GENE-17335932 XB-GENE-947780
Gene Symbol gnas gnas.L gnas.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 407931
399059
394414
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gnas gnas.L gnas.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GNAS OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gnas MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gnas Ensembl
zebrafish
ZFIN, AGR gnas ZFIN Ensembl
chicken
GEISHA GNAS Ensembl
fruit fly
worm
Publications
First Chemical composition of an oestrogen-induced calcium-binding glycolipophosphoprotein in Xenopus laevis., Biochem J 1971  
Most Recent Experimental approaches to identify selective picomolar inhibitors for carbonic anhydrase IX., Curr Med Chem 2020  
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 5 terms 6 terms
PANTHER gnas
KEGG Pathways K04632 K04632 K04632
KOG [T] G protein subunit Galphas, small G protein superfamily
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gnas
Antibodies Gnas Ab1 , Gnas Ab2 , Gnas Ab3 Gnas Ab2 , Gnas Ab3 Gnas Ab2 , Gnas Ab3
Morpholinos (on-target & off-target) gnas MO1 gnas MO1 gnas MO1
ORFs gnas ORF1 , gnas ORF2 MGC68706 ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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