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Summary Expression Gene Literature (12) GO Terms (14) Nucleotides (109) Proteins (27) Interactants (130) Wiki
XB-GENEPAGE-948845
Gene Symbol: xiap

Gene Name: X-linked inhibitor of apoptosis

Synonyms: api3 , ilp1 , miha , xlp2 , birc4 , xxiap ( Add synonyms , Nomenclature history )

Gene Function: Apoptosis inhibitor IAP1 and related BIdomain proteins

Protein Function :
Multi-functional protein which regulates not only caspases and apoptosis, but also acts as an E3 ubiquitin-protein ligase mediating ubiquitination and subsequent proteasomal degradation of its target p...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: X-linked lymphoproliferative syndrome 1 [+]

OMIM: LYMPHOPROLIFERATIVE SYNDROME, X-LINKED, 2; XLP2 [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
 
Xenbase Gene ID XB-GENE-948846 XB-GENE-948852 XB-GENE-17342551
Gene Symbol xiap xiap.L xiap.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 594971
733235
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL Swiss-Prot TrEMBL RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine xiap xiap.L xiap.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards XIAP OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Xiap MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR xiap ZFIN Ensembl
chicken
GEISHA BIRC8 Ensembl
fruit fly
worm
WORMBASE
Publications
First XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway., EMBO J 1999  
Most Recent NCBP2modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models., PLoS Genet 2020                          
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 10 terms 0 term
PANTHER xiap
KEGG Pathways K04725 K04725
KOG [DR] Apoptosis inhibitor IAP1 and related BIdomain proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks xiap
Morpholinos xiap MO1 , xiap MO2 xiap MO1 , xiap MO2 xiap MO1 , xiap MO2
ORFs xiap ORF1 xiap.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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