Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (9) GO Terms (15) Nucleotides (103) Proteins (23) Interactants (108) Wiki
XB-GENEPAGE- 948845

Gene Symbol: xiap

Gene Name: X-linked inhibitor of apoptosis

Synonyms: api3 , ilp1 , miha , xlp2 , birc4 , xxiap
Add Xenopus synonyms , Nomenclature history


Gene Function: Apoptosis inhibitor IAP1 and related BIdomain proteins

Protein Function:
Multi-functional protein which regulates not only caspases and apoptosis, but also acts as an E3 ubiquitin-protein ligase mediating ubiquitination and subsequent proteasomal degradation of its target p...[+]


Interactants: YYY

OMIM Disease Associations: LYMPHOPROLIFERATIVE SYNDROME, X-LINKED, 2; XLP2
 
Xenbase Gene ID XB-GENE-948846 XB-GENE-948852 XB-GENE-17342551
Gene Symbol xiap xiap.L xiap.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.37821 Xl.5264 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine xiap xiap.L xiap.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards XIAP OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Xiap MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN xiap ZFIN Ensembl
chicken
GEISHA XIAP Ensembl
fruit fly
worm
WORMBASE
Publications
First: XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. [EMBO J 1999]
Most recent: Global decay of mRNA is a hallmark of apoptosis in aging Xenopus eggs. [RNA Biol 2017]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 12 terms 0 term
EC
PANTHER xiap
KEGG Pathways K04725 K04725
KOG [DR] Apoptosis inhibitor IAP1 and related BIdomain proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino xiap MO1 , xiap MO2 xiap MO1 , xiap MO2 xiap MO1 , xiap MO2
ORF xiap ORF1
Affymetrix 1.0 Str.37821.2.S1_a_at [+] Xl.5264.1.A1_at
Affymetrix 2.0 Xl2.5264.1.S1_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556