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Summary Expression Gene Literature (11) GO Terms (1) Nucleotides (108) Proteins (23) Interactants (126) Wiki
XB-GENEPAGE-948845

Gene Symbol: xiap

Gene Name: X-linked inhibitor of apoptosis

Synonyms: api3 , ilp1 , miha , xlp2 , birc4 , xxiap ( Add synonyms , Nomenclature history )

Gene Function: Apoptosis inhibitor IAP1 and related BIdomain proteins

Protein Function :
Multi-functional protein which regulates not only caspases and apoptosis, but also acts as an E3 ubiquitin-protein ligase mediating ubiquitination and subsequent proteasomal degradation of its target p...[+]

Interactants: Loading ...
Disease Ontology: X-linked lymphoproliferative syndrome 1 [+]

OMIM Diseases: LYMPHOPROLIFERATIVE SYNDROME, X-LINKED, 2; XLP2 [+]

 
Xenbase Gene ID XB-GENE-948846 XB-GENE-948852 XB-GENE-17342551
Gene Symbol xiap xiap.L xiap.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine xiap xiap.L xiap.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards XIAP OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Xiap MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR xiap ZFIN Ensembl
chicken
GEISHA BIRC8 Ensembl
fruit fly
worm
WORMBASE
Publications
First XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway., EMBO J 1999  
Most Recent Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling., J Cell Sci 2018          
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 1 terms 0 term 0 term
PANTHER xiap
KEGG Pathways K04725 K04725
KOG [DR] Apoptosis inhibitor IAP1 and related BIdomain proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino xiap MO1 , xiap MO2 xiap MO1 , xiap MO2 xiap MO1 , xiap MO2
ORF xiap ORF1 xiap.L ORF1
Affymetrix 1.0 Str.37821.2.S1_a_at [+] Xl.5264.1.A1_at
Affymetrix 2.0 Xl2.5264.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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