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Summary Expression Gene Literature (2) GO Terms (5) Nucleotides (151) Proteins (26) Interactants (216) Wiki
XB-GENEPAGE- 950594

Gene Symbol: cpsf2

Gene Name: cleavage and polyadenylation specific factor 2

Synonyms:
Add Xenopus synonyms , Nomenclature history

Gene Function: mRNcleavage and polyadenylation factor II complex, subunit CFT2 (CPSF subunit)

Protein Function:
CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. In X.l...[+]


Interactants: Loading ...

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-950595 XB-GENE-17346907 XB-GENE-950598
Gene Symbol cpsf2 cpsf2.L cpsf2.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.65992 Xl.3876
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 3 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine cpsf2 cpsf2.L cpsf2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas058k09      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CPSF2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Cpsf2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN cpsf2 ZFIN Ensembl
chicken
GEISHA CPSF2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides. [PLoS Genet 2006]
Most recent: Biochemical characterization of Pumilio1 and Pumilio2 in Xenopus oocytes. [J Biol Chem 2011]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 0 term 5 terms
EC
PANTHER cpsf2
KEGG Pathways K14402 K14402
KOG [A] mRNcleavage and polyadenylation factor II complex, subunit CFT2 (CPSF subunit)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino cpsf2 MO1 cpsf2 MO1 cpsf2 MO1
Affymetrix 1.0 Str.10927.1.S1_at Xl.3876.1.S1_at
Affymetrix 2.0 Xl2.3876.1.S1_at

Symbol legend[+]

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