Gene Symbol: hmgxb4 Gene Name: HMG box domain containing 4 Synonyms: xHMG2L1, hmg2l1 Add Xenopus synonyms Gene Function: negative regulator of Wnt signaling Interactants: lef1(1) , map3k7(1) , mapk1(1) , nlk(1) , nlk.2(1) , nr2c2(1) , View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001030384|Xenopus (Silurana) tropicalis HMG box domain containing 4 (hmgxb4), mRNA GTGGGATGTGCAGAGTTCAGACAATGTGACATTTACATTCTGGTGAAAAACTGAGGACTGTTATAGCCATGTCCTTCCGCGATTTAAGAGAATGCATAGATTCAGAGCGTGGAATGGAGGATGTAGGTTTGGCAGCTGGCAGAAGCCAACGGGAGAAGAAGAGATCATATAAAGATCTGCTGCGTGAGGAGGAGGAAATTGCTGAGCAAGTTCGGAAGTCCTCTAAAAAGAGATCCAGGGAGTTAGATTTATTCTTGGCATCTGAATCACACAAGAAGAAGAAAAAGCATTTAACAGATGACTATCATGCAGATACCCCTTCACCAGACCTTGCAAAGAAGAAAAAGAAAGCTTTACTTCCCAGTCCTGCTCCTCCTTCTTCTTCAGACACAGCTATGGATCTTCTGAAAGCCATTACTTCTCCTCAAGTGGATACCTCCACCACACACCTCCCCAAGAAACCAGAGAAAATACTGGCAACTCCTGTTAACTTTTCATCCCCCAGTCAGTCATCACACAAAGAGCATCACAAAAAAATTGGAGAAGTATCTGGGGATGATTCTTCCCATCGATCAAAGAAATCAAAACCTCTTACTCTGCGTGAGCCAGATGGCTTAAGGATGAAACTAATATTGTCTCCCAATGAAAAGAGTGAAGAAGAGTCTGCCTCACCACAGGGGGGTCCAGGACATAGTGAGGGTGCATCTTCTAAGAAAACCAGCAAGAAAACAGGAAGAGAGGAAACCGAGAGCAGATCTAGCCACAAAAAACACAAAAAGGAATCTCATACACCACGGTCTGGTGGTACACCTGATTCGGCATCATCCACTGGTGGGGAGCTGGAAGCTGGGGAACTGATCATTGATGATTCTTTCCATGAAATGAAAAAAAAGAAGAAATCAAAGAAAAGCAAAAAGAAAAAAGACAAACACAAGGATGAAAAACACAGAAAACATAGCAAAAGTAAAAGAGAGCATGAGGGGGAGGAAAGACCAACGCAAATTGCCTCTCCTGTGCTGCCCTCACCACCTCCTCCCACTGCTACAACACCAACTTCACCACCATCTGTACCTCCACAAGCACTCATTACTCACGCAGAAGAACAGTTGGATAAGAAGAAGAAAAAAGAGGACCCAGAGAAGCCCAAAAAGAAGAATATGTCTGCTTACCAGGTCTTCTCCAAAGAATATCGAGGTAGCATCATTGCAGAGCACCCAGGAATTGACTTTGGGGAGTTAAGTAAGAAACTTGCTGAGGTGTGGAAGCAGCTTCCGGAAAAAGATAAACTTGCTTGGAAACAAAAGGCTCAGTATCTCCAGCACAAACAGAACAAAGCTGAGGCCACTACTGTGAAACGGAAATCCAGCTCCTCTGAGTCTGCTGCAAGGAGCAAAGGCTCATCTTCCGGTCTCCCCTCCCCAAACAAGAAGTCACCAACCAGTGTTGTTTCCTTCTCCACCTCTCCAGCCAAGGTCCCTGACACAGAGCCAATTGATGTAGCTGCACATTTGCAGCTGCTAGGGGAGTCTCTAAGCCTAATCGGACACCGCCTCCAGGAGACAGAAGGAATGGTTGCTGTCTCTGGCAGTCTGTCTGTGCTACTGGATTCTATCCTGTGTGCCCTGGGCCCATTGGTATGTCTTACAAGTCATGTGCCACAGCTCAATGCTTGCCCCAAGCAAATACTGTCAAACACATTGGACAACATTGCCTACGTGATGCCTGGCTTATGACAGTAAAGGACTTGTTGGTAAAAGAGAGAATAAATAAAGGGCATCAGATGCCAGATTTTATATTTGTACAGTATTAATGGTATACAAAGTATACAGTATTTTATACTCACTGTCTTTTATTGTCTTTTAGAAGTCAGCACTGAATACATCTATTTATTTGGCCTGGGTGCAGGTACACTGGTGTTGAAATGCATACTTGCACATTTCAGGGCTGAAATCCTCTCCGTGTACCTGCACCCTGCCCAACGCAGTGGCACCTGGTGCAGACATATGAGAGGGCTGATTCTTACCTTGCATTGATCTGCAGGCCGAAAAACAGCCCATTGTTGCATTAGCCTTATATGAGGGCTTATATACATATAGTAATAAAATAATTTTAAAAATAGAATCTACTTCCTGTTTGCTGGACCATATCAGATAGCATTCTTAATTTCACGTTGAAGAGGAGCAGACTAGAATCACAAAGAAATAAAAAGACCTAATGTGAATGACCCATGGCAGAGCTGATTGGATTACTTCTATGTAGCATATAAGAAAAGTACAGTGAATTTCAGCTGCGTGTGCCTGCAACCGGGCGGGTTCATTGCTCCCTGGGGCAGCCACAACGAGAATGTTTGTTTTTTCAAGTGTACGGACGTATTGTTAGCCTTCGCTTATCGGCAGGCTGACAATATGCCCTGTTTGACCTTGCCCTAAATCTTAAATATAAATGCCTTTTTTACCCATCAAATTTAGTCTTCCTTCAACATCATAGTTTTGAATTTATAACATTTTTCTAAGAAGGTCAAATACTGCCTTTAAATGAAGGGTCTTCTAGTGTTGTTTTAGTAAGGTTCCATAGTTTTTTCTCCTGCAGTTTTCTGCTGGCTGAGAATTACCCATGACTGCCTCCTGCACCTCTAATTTACACTTACAAAAACAGGGACCAATGATTAGATCATACAGCAACGGGGCTATAGAGACCCATCAAACCTATTTAATAGATATCTGGTGGATTTTCAGATTGATTTTGCTCATACGGGCCTTCCGAAATGACTGCAAACAGACCAATAAGCTGTTGACTAGGTCTGGAGGGGCTGAGTTGGCTGCTTTTACAGCAGGGAAACATCAACGCTTTTCTCAGTAAATATATTTCTAATGGGGCTATTGACATGAAATTTATACCAGATGTCGGCAACAACCCAAGTAATCCACACATATAAAGAAATCAAAACAAATTAGTCCATAAATTAAGTTATGTGTAGTAAAGTGGAATGATACAGGGAAGAAGTATTGAACTCACAGTTATTGAAATGTATTTAATACTTAGTAGAAAAGCCTTTGTTGGCTTCAAGGTGCCTCCTGTGTGGAGAAACTAGTTTCATGCATTGCTCAGGTGGGATTTTGGCCCGTTCTTCCACACAAACTCAGTGCCAATTTTCTTAGAATGTAATTTTCAGCCGTTTGGGTTAGCTACACATTATGTCAGTGATTCCAAAACTGTGGGTCTGAGGCCTGGAGCAATGGCAGGGTGGTTGAATTATGGTAGGATTTGGGGGAAAGAGCCTATTTGCTCTCCTAGATACACTTGAACGCACAGTAAAACAAAAAAAGGTTATTTGTGGTAAACCCTTTCATTTGCTGTCCTGGGTATACTTAGGCCTGGGCCTAGTGCAGCATGCCGCCCAGCTGCATCTAAATTGGTTCTGAAAGTACTGGCAACACCTAGGAGATTGGTTAGCTCTTTAAATCTCCCATGCCAGTCTCCAGACCCAATGAGGAAGGACTTGCACAGGTACACATTCTCACAAAAGGGGAGGGGGGGTTTCAATGAGCGGTGCTGGCCTAGGAGCACCCGCTGATTAAATCTAGGCCTGGTCTGAATATTTAATACACAATCATTTTCTGTACTTGTAACCTCGTTATGAACTAAGGGGGTGCCCTGAGCAACGACTGTGTAAATATTGGATTGAATTCTTTATTTATCTAATTGATTTGGATGAAAGATATAATGAGCGGGAGGGCGTGTGTGTAGGAAAGGCTGTAATTGTTATATAATAATTACATCATGCTTTCAGTATTGCAAGTTCTAAACAAAATAAAAGATGTAGGAAAACTGCTTTCTTTTTGTATTGTAACATTACCAACTGATCTTATATTTTATTTCAATGACACAGAAGTGTAAACAGTCCTGCATTGTCTTTGTGTATCATTTTTAAGATTGTTTTTAATAGTTTTTTATTAATAAAAAATAAAACATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001089277|Xenopus laevis HMG box domain containing 4 (hmgxb4), mRNA GAATTCGGCACGAGGGAAAAGACACCAGAAGGAGCTGTACCAGCATATCTACTGGACAGAGAGGGTCAGACTCGAGCCAAAGTTCTATCTAATATGATAAAGCAAAAGAGGAAAGAAAAAGCTGGTAAATGGGAAGTACCGTTGCCTAAAGTGCGTGCTCAAGGAGAGACAGAAGTTCTGAAAGTAATCCGCACTGGCAAAAGAAAGAAGAAGGCCTGGAAAAGAATGGTCACCAAAGTGTGCTTTGTTGGTGATGGCTTCACCCGAAAGCCTCCCAAGTATGAAAGGTTCATCAGACCTATGGGCTTACGTTTTAAGAAAGCACACGTGACGCACCCGGAGCTTAAAGCCACATTCTGCCTTCCTATTCTTGGTGTGAAGAAGAACCCCTCCTCTCCACTCTATACAACATTAGGTGTCATTACTAAAGGGACAGTTATAGAGGTGAACGTAAGCGAACTTGGTCTGGTCACACAAGGAGGCAAAGTTGTTTGGGGTAAATATGCACAAGTCACAAATAATCCAGAAAATGATGGCTGTATAAATGCAGTTCTGCTTGTATAACATGAACTTTCCTGGAAAATTGTGTAATAAAATGGATTTCCCACTAAAAAACAGGACTGCAGGCTGAGTGTGCAGGGGAATTAACATGCAGGGACTCTAGCAACGCAGTCATCCAAGTTGTGTCCACAAAGTGACGTTTACATTCTTGTGAGAAACTGAGGAAGGCTTAGCCATGTCCTACCGTGATTTAAGAGAATGCATAGATTTGGAGCGTGGAACGGAGGATGTAGGTTTGGCTGCTGGCAGAAGCCAAAGGGAAAAGAAGCGATCATATAAAGATCTGCTGCGTGAGGAGGAGGAAATCGCTGAACAAGTCCGGAAGTCCTCCAAAAAGAGATCCAAGGAATTAGATTTATTTTCGGGAAACGAATTGCACAAAAAGAAGAAAAAGCATTCTTCAGACGACTATCATGCAGATCACTCTACAGATTCTGCAAAGAAGAAAAAGAAAACTTCACTTCCTAGTCCTTCTTCTTCAGACACGGCTATGGATCTTCTGAAAGCCATTACCTCTCCCCAAGCAGATACCTCCACCACACACCCCTCCAAGAAGCCAGAAAAAATCCTGGCGACTCCCATCAGCTTTTCATCCCCCAGTCAGCCACCTCATAAAGACTATCACAAAAAAAGTGGAGAAGTATCTGGGGATGATTCTTCCCATCGATCAAAGAAATCAAAACCTCTTACTCTGCGGGAGCCAGATGGCTTAAGAATGAAACTAATTATGTCTCCCAATGAAAAGAGTGAAGAAGAGGCAGTCTCACCACAAGGGGGTCCAGGACATAGTGATAGTGCATCTTCTAAGAAAAACAGTAAGAAATTGGGAAGAGAAGAAATTGAGAGCAGGTCCAGCCACAAGAAACACAAAAAGCAATCCTATACACCACGGTCTGGTGGTACGCCTGATTCAGCATCATCCACTGGTGGAGAGCTGGACGCTGGGGAACTGGTCATTGATGACTCTCTTCGCGATATGAAGAAAAAGAAGAAATCAAAGAAAAGCAAAAAGAAAAAAGATAAACACAAAGATGAGAAACACAAGAAACATAGCAAAAGTAAACGAGAGCATGAGGTGGAGCAAAGTCAAACACAAATTGCCTCTCCTGGGCTGCCTTCACCTCCTCCTCCCCCTGCTACAACACCACCAACTTCACCACCATCCATACCTCTTCAACCACAAGCACTCGTTACTCACACAGAAGAGCAATCCGATAAGAAGAAGAAAAAAGAGGACCCAGAGAAGCCCAAGAAGAAGAATATGTCTGCTTACCAGGTCTTTTCCAAAGAATATCGAGTCAGCATCATTGCAGAGCACCCAGGAATTGACTTTGGGGAGCTAAGTAAGAAACTTGCTGAGGTTTGGAAGCAGCTTCCTGAAAAAGATAAACTTGTTTGGAAACAAAAGGCTCAATATCTCCAGCACAAGCAGAACAAAGCAGAGGCCACTACTGTGAAACGTAAATCCAGCTCCTCTGAGTCTGCTCCAAAGAGCAAAGGCTCATCTTCTGGTCTTGTCTCCCCAAACAAAAAGTCACCAACCAGTAGTGTTGCCTCCTTCTCCACCTCTCCAGCCAAGGTCCCTGACACAGAGCCAATTGATGTAGCTGCACACTTGCAGCTGCTAGGTGAATCTCTGAGCCTGATTGGACACCGTCTTCAGGAGACAGAGGGAATGGTTGCTGTGTCTGGCAGTCTGTCTGTGCTACTGGATTCCATCCTATGTGCCCTGGGCCCATTAGTATGTCTCACAAGTCATGTGCCTCAGCTGAATGCCTGCCCCAAGCAAATCCTGTCGAATACATTGGACAACATCGCCTACGTGATGCCGGGCTTATGACCGTGATGGACTTGCCAGTAAAGAAAAGAATAAATAAAGGGCATCAGATGCCAGATTTTATAGTTGTACAGTATTGTATACTTTTTGCGTCTTTTAGTTCATTTTAGAAGGCAGCTGTGTATACTAAGCGTTATTTTATCACGAATAATTTTGCTCCACTCATCATTGCTAAAGGTTGTCAGTTTGCTCTGTTACATAGTACAGGTATGGGATAAATGATCTAGA
Protein		Refseq >NP_001025555|HMG box-containing protein 4 [Xenopus (Silurana) tropicalis] MSFRDLRECIDSERGMEDVGLAAGRSQREKKRSYKDLLREEEEIAEQVRKSSKKRSRELDLFLASESHKKKKKHLTDDYHADTPSPDLAKKKKKALLPSPAPPSSSDTAMDLLKAITSPQVDTSTTHLPKKPEKILATPVNFSSPSQSSHKEHHKKIGEVSGDDSSHRSKKSKPLTLREPDGLRMKLILSPNEKSEEESASPQGGPGHSEGASSKKTSKKTGREETESRSSHKKHKKESHTPRSGGTPDSASSTGGELEAGELIIDDSFHEMKKKKKSKKSKKKKDKHKDEKHRKHSKSKREHEGEERPTQIASPVLPSPPPPTATTPTSPPSVPPQALITHAEEQLDKKKKKEDPEKPKKKNMSAYQVFSKEYRGSIIAEHPGIDFGELSKKLAEVWKQLPEKDKLAWKQKAQYLQHKQNKAEATTVKRKSSSSESAARSKGSSSGLPSPNKKSPTSVVSFSTSPAKVPDTEPIDVAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLLDSILCALGPLVCLTSHVPQLNACPKQILSNTLDNIAYVMPGL UniProtKB	Refseq >NP_001082746|HMG box-containing protein 4 [Xenopus laevis] MSYRDLRECIDLERGTEDVGLAAGRSQREKKRSYKDLLREEEEIAEQVRKSSKKRSKELDLFSGNELHKKKKKHSSDDYHADHSTDSAKKKKKTSLPSPSSSDTAMDLLKAITSPQADTSTTHPSKKPEKILATPISFSSPSQPPHKDYHKKSGEVSGDDSSHRSKKSKPLTLREPDGLRMKLIMSPNEKSEEEAVSPQGGPGHSDSASSKKNSKKLGREEIESRSSHKKHKKQSYTPRSGGTPDSASSTGGELDAGELVIDDSLRDMKKKKKSKKSKKKKDKHKDEKHKKHSKSKREHEVEQSQTQIASPGLPSPPPPPATTPPTSPPSIPLQPQALVTHTEEQSDKKKKKEDPEKPKKKNMSAYQVFSKEYRVSIIAEHPGIDFGELSKKLAEVWKQLPEKDKLVWKQKAQYLQHKQNKAEATTVKRKSSSSESAPKSKGSSSGLVSPNKKSPTSSVASFSTSPAKVPDTEPIDVAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLLDSILCALGPLVCLTSHVPQLNACPKQILSNTLDNIAYVMPGL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.822	Xl.78223 [+] Xl.57325
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		16 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	HMGXB4
mouse		MGI	Hmgxb4	All(1) Targeted, other(1)
zebrafish

Publications
First:		Negative regulation of Wnt signalling by HMG2L1, a novel NLK-binding protein. [Genes Cells 2003]
Most recent:
		View All Papers

Functional Ontologies
GO: Molecular:		DNA binding
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		chromatin nucleus
EC:
KOG:		[R] HMG box-containing protein

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.822.1.S1_at	Xl.19164.1.S1_at
Affymetrix 2.0			Xl2.5160.1.S2_at [+] Xl2.19164.1.S1_at

Symbol legend[+]

- Blast this sequence
   - Literature Or Expression Images