Please note upcoming maintenance times for Xenbase - times are EST:

Wednesday 12-Dec-2018 before noon: BLAST, FTP (Xenbase will be partially functional)
Thursday 13-Dec-2018 before noon: Wiki, GBrowse, JBrowse (Xenbase will be partially functional)
Friday 14-Dec-2018 starting at 5 pm through weekend: Xenbase site and database (Xenbase will be completely down)

Click on this message to dismiss it.
Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (3) GO Terms (6) Nucleotides (500) Proteins (19) Interactants (333) Wiki
XB-GENEPAGE-951909

Gene Symbol: ndrg2

Gene Name: NDRG family member 2

Synonyms: ( Add Xenopus synonyms , Nomenclature history )

Gene Function: Differentiation-related gene 1 protein (NDR1 protein), related proteins

Protein Function :
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.

Interactants: Loading ...
Disease Ontology:

OMIM Diseases:
1/4
 
Xenbase Gene ID XB-GENE-951910 XB-GENE-17345856 XB-GENE-951915
Gene Symbol ndrg2 ndrg2.L ndrg2.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Swiss-Prot Refseq Swiss-Prot TrEMBL TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images                   Ensembl In situ: Single cell: RNA-Seq:  
Data Mining tropicalis laevis.L laevis.S
XenMine ndrg2 ndrg2.L ndrg2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NDRG2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ndrg2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ndrg2 ZFIN Ensembl
chicken
fruit fly
worm
WORMBASE
Publications
First (NDRG2) stimulates amiloride-sensitive Na+ currents in Xenopus laevis oocytes and fisher rat thyroid cells., J Biol Chem 2007  
Most recent Exploring the phosphoproteome profiles during Xenopus egg activation by calcium stimulation using a fully automated phosphopeptide purification system., J Biochem 2016  
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 0 term 4 terms
PANTHER ndrg2
KEGG Pathways
KOG [S] Differentiation-related gene 1 protein (NDR1 protein), related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
ORF ndrg2 ORF1 ndrg2.S ORF1
Affymetrix 1.0 Str.6843.1.S2_at [+] Xl.2279.1.S1_at [+]
Affymetrix 2.0 Xl2.2279.1.S2_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.10.0


Major funding for Xenbase is provided by grant P41 HD064556