[provisional- machine annotated only] Gene Symbol: fbxo43 [Predicted: Source is Human Entrez Gene] Gene Name: F-box protein 43 [Predicted: Source is Human Entrez Gene] Synonyms: erp1, emi2, Xerp1 Add Xenopus synonyms Gene Function: Predicted E3 ubiquitin ligase Interactants: cdk1(8) , mos(8) , ccnb1.2(7) , plk1(7) , fbxo5(6) , mapk1(5) , pold1(5) View All	1/2

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002934410|PREDICTED: Xenopus (Silurana) tropicalis F-box protein 43 (fbxo43), mRNA GGCCAGGGATTGGAGTTGCCATAGGAAGGCAGACCTGTTCTTTAGCCCGGCTAATAAAATGTTAATGCGGTTTGGTGTATCCCTCTGGCACCACTGACACTTGCCACTAGCGATATCCTCCTTCTATATGGGCATTTCTGTATTGGCTTCATTGCTATGGATTCCAGGACTGACCTGGGCTGCTGGGGCTTCTTTCATGGACTGAAGGCATACAGAAGAAAGAAGCAAGAGATGGCACAAAGATGCTCTCTCTTAGACAATTTTGCTCTGCATCACTCGACAGACCCAACTGGGGCAACGAAAAAGGTTGACCGCCAAGATCATTCCATATCGGTGTCGCAGGACAGTGGCTACAGTGACTCTCTAAAGGGATTCAGCCCAGACTCTCATAAAAGTGGTCATTTCTTGGAAACTGTGACTGAGGGATATGAAAATTCAGAAAATATAGATCCTACCTTGATACTCTCTCCAATTAAACATGAAATCCCTTGGGGAGCAGATACAAGGGAATCCAAGCAGCTTGCACCAATTTATGAAACCCCCCGCTTTAGTAAGAAGGATTTCTCCCTTCGTAGAAGGCTGCTCATTTCTAAAGCTACCTCAGGAGGAAACTTAGATTTTGATGCATCTGTGTGTTCAACAGAAAGTTATGGCAGGGAAAAGTCCCTTAAGAGTGTTCCAAGTTTTGAGGGAAGCCTTTCAAATAGCTTTGTAGATTCCCCAAGAGACAGCAGCTATAAACCAATAGCCACCAGCACTTTAAAGACTGAATCTGAATCTGGAACATCTTGCAAAAAATGGAGACTATCTTTTGCTCAGCAGAGGAGTTCTACCTTAGATGATTCTAAAAGTGACAGTATTTCTTTACCGGAAGTGGAAAATATATCTCCAGTTCAGCATTCACTGGCTAGTTCAACTGATGACAGCATCCTGTATGAAGAGAATATATTCGGAGCACCAACAACTCCAACCTGTAACTTAATTGCCAAAGAAGAGTTTCAGACTCCCATTAGTAACCTTGCAGCAAACTTTAGCTTTAATTTATGCACTCCGAGCATCACCCATGTCAGTGACTTTGAGATCTCTGTAACCGAGGACAGCGCATTTCACTCTCTCAGCCTGGACAAGTCACAAGACTCCATCACTGATCATGAGGGTTCTTTTCAAGAACTAATTCAAAAGCCCAGAGTGACCCCCAAAGCAGTTCACAATAAAAATCGTTCCAGGAAACTAGATCGATGTAGGAGATTATCCACCCTTAGAGAGCGTGGATCTCAGTCTGAGGTAGAGGAAGAAGGCAATGAGGCCCCTCTGCTAAGTTCTGCCTACAAGTCAAAGGTTGCAAGAGCGTCCGTAGATGAAGAAAATGAATTTAGCTCGGATGATAGCAGAGTCAATTCTCTTTTAAGCATCGATGATTTAACCGGGAAACCTGCTCTCAGAGTTCTCCATGAAATGCTGCTGAGAAGCACACGCAAAAGACCCCAACAGGCTACCGTGCAAGATCTCCTGGGTAGTTCGGGTTGTTTTGAATTACCAGAGGATTCTCTTTCAAGACTTATTGGCAGGAAAATGGGTTTAGTCACATTTGATATTTTAGCTGAACTGAAATACAGAAACTTAAAGCACATAATTGCATCCATTTTGGGCCTCATGAATGTGGAAAGTATTTGCAGTATGTGTAGGGTTAGCAGAGACTGGCGTGATATTATTCTCCAAGATAAGAGCGCACATCAGAGAAGGAAAGCTTACATGAGAAGGCTAAAAACTGAAGCTGAGCAAGGACGGCAGCAATCGTTCGAAGACTCTGCAACCACATTAAACATTTTAAGCCGATCGGCTCTAAAATCTGTTCAGATTCAAGCTAGGACAGCATTTCAGACCCCAACTTCTTCCTTGACTCCTGGAGATAACAAATCCATCCAGTCAGCAAGCAAACACCAAGAATATCTTCAGGTTGCCAAAACTCTGTTTACAGATGAAGCTTTAAAACCATGTCCGCGGTGCCAGTTCCCTGCAAAATATCAAGCACTCAAGAAAAGAGGCAAGTGCAGTAGAAAAGACTGTGGCTTTGATTTCTGCGTCCTTTGTCTGTGCACTTTCCATGGTTCAAAGGAATGCGGCACTGGATCCGCAAAAAGGATACCGAAAAAAGAGGCGCTTCCTGGAAGTGCCCAAAGCAAAAGGAATTTGAAGAGACTTTAAAGTTTATCATCCAGCAGATCCCTGTTTTATCAGTTTTTTTTTTTTTTTTTTTTTTTCCTTTATTTTTATGAGTGGGGGCGGTTGTATGACCAGAGGCTTTATAAATGTACATTTGTTCTGTAGATTCTTTGGTGTGTTTAATGATTGCAGTACATTCACATATTTAAATACTTTGGTGCAATTTAGGGTGAAAATAAAATTTGGAATGCAAGGTACACTTTGCAACCATAGCACTTAATGCCACTATTTTGCACACAAGGTGTGTATATCTGTGACTGTGCTGTGATGATTGAAAGCTCCCACAGATTTTATGTGTATATATACATTCATTTGTTTAATGTTGCAAGTCTTGCTTCTTTTATAGTTTCCTTTTATGAAATAAGTATGTTGTGTCTCTATTCAGCTGCATTTTTAATAAAATATATTTTAGAATAC	Refseq >NM_001099868|Xenopus laevis F-box protein 43 (fbxo43), mRNA AAGAAACAAGAGATGGCAAATCTCTTAGAGAATTTTGCTGCCCATCACTCAATGACGGCTGGGGCAAAGAAGAAGGCTGACCACCAAGATACTTCAGTGTCGCAGGACAGTGGCTACAGTGACTCTCTAAAGGGATTCAGCCCAGACTCTCATAAAAGTGGTAATTTCTTGGAAACCGTGACAGAAGGGTATGAAAATTCAGAAAATATAGATCCCACCTTGATACTGTCTCCAATAAAATATGAACTCTCTTGGGGAGCAGACACAAGGGAATCCAAGCAGCTTGCTCCACTTTATGAAACCCCTCGAGTTGGGAAGAAGGAATTCTCACTTCGCAGAAGGCTGCTCATTTCTAAAGCTACCTCGGGAGGAAATTTAGATTTTGATGTGTCTGTGTGTTCAGCAGAAAGTTGTGGCCGGGAAAAGTCCCTTCGGCGTATACCAAGTCATGAGGGAAGCCTTTCCAATAGCTTTGCAGATTCCCCAAGAGACGGCAGCTATGAGCCAATAGCCACCAGCACTTTAAAGACAGAGTCTGAATCTGGAACATCTTGCAAAAAATGGAGACTATCTTTTGCTCAGCAGAGGAGTTCCACCTTGGATGATTCTAAAAGTGACAGTATTCCTTTACCAGAAGTGGAAAATATATCTCCGGTTCAGCATTCATTGGCTAGTTCAACTGATGACAGTATACTGTATGAAGAGACGATATTCGGAGCACCAACAACCCCAACTTGTAATTTTATTGTCAAAGAAGAGTTCCAGACTCCTATTAGTAACCTTGCAGCAAATTTTAGATTTAATTTATGCACTCCCGATGTTGGCCATGTCAGTGACTTTGATATCTCTGTAACTGAGGACAGCGCATTTCACTCTCTTAGCCTGGATAAGTCACAAGATTCCATCACTGATCACGAGGGTTCTTTTCAAGAACTAATTCAAAAACCCAGAGAAACCTCCAAAGCCGTTAACAATAAAAGTCGCCTCCGCAAATTAGATCGGTGTAGGAGACTATCCACCCTTCGAGAGCGTGGATCTCAGTCCGAAGTAGAGGAAGAAGGAAATGAGGTTCCTGTGCTAAGTTCTGCTTATAAGTTAAAGGTTGCAAGAGCGTCGGTCGATGAAGAAAATGAATTCAGCTCAGATGAAAGCAGAGTCCATTCTCTCTTAAGCAGCGATGACTTAACAGGAAAACCTGCTCTCCGTGTTCTCCATGAAATGCTGTTAAGAAGCACACGGAAAAGGCCCCAACAGGCCACCGTGCAGGATCTCCTGGGTAGTTCGGGTTGTTTTGAATTACCAGAGGATTCTCTTTCAAGACTTATTGGTAGGAAAATGGGTTTGGAGACATTTGATATTTTAGCTGAGCTGAAAAACAGAAATTTAAAGCATATACTTGCATCAATTTTGGACCTCGTGAACGCTGCAAGTATTTGCAGTATGTGTAGAGTTAGCAGAGATTGGCGTGATGTTGTTCTCCAAGATAAGAGTGCACATCAGAGAAGGAAAGCATACATAAAAAAACTGAAAACTGAAGCTGAGCAAGGACGGCAGCTATCCTTTGAAGACTCTGCAACCAGACTAAATATTTTAAGTCGATCAGCTCTAAGATCTGTCCAGATTCAAGCTAGGAGTGCATTTCGGACACCGACCTCCTCCTTGACTCCAGGAGATAACAAATCCATCCATTCAGCAAGCAAACACCAAGAATATCTTAAGGTTGCCAAAACTCTGTTTACGGATGAAGCTTTAAAACCATGTCCACGGTGCCAGTACCCTGCAAAATATCAAGCACTAAAGAAAAGAGGGACTTGCAGCAGAAAAGATTGTGGCTTTGATTTCTGCAGCCTCTGTCTGTGCACTTTCCATGGCTCAAAGGAATGCGGCACTGGATCAGCAAAGAGGATCCCTAAAAAAGAGGCGCTTCCTGGAAGTGCCCAAAGCAAAAGGAATTTGAAGAGACTTTGAAGCTAGTCTTCCTGCCAGATACCCATTTTATTTATATATATATATATATATTTATTTTTTAGGGGTTTATGGGTGGGGCTTTGGGGGTGTGTATGATCCGAAGCTTTATAAATGTAGATTCTGTGGTTTGTTTAAAGATTGCAGTACACTCGCATATTTAAACACTTTGGTGCAATTTAGGGTGAAAATAAAATTTGGAATGCAATGTACACTTTGCAACCATAGCACTTAATGCCAGTATCTTGCACCTGATGTTTGTGTATTTGTGACTGAGCTGTGATGTTTGAAATGTCCCACAGATTTTATGTGTATATACATTCATTTGTTCAATGTTGCCATGTCTCTTGCTTGTTTTAGATTTTTCTTTTATAACATGATGAAGTATGTCGTCTACCTATTTAGCTGCATTTTTAATAAAATATTTTAGAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		NCBI Protein >XP_002934456|PREDICTED: f-box only protein 43 [Xenopus (Silurana) tropicalis] MDSRTDLGCWGFFHGLKAYRRKKQEMAQRCSLLDNFALHHSTDPTGATKKVDRQDHSISVSQDSGYSDSLKGFSPDSHKSGHFLETVTEGYENSENIDPTLILSPIKHEIPWGADTRESKQLAPIYETPRFSKKDFSLRRRLLISKATSGGNLDFDASVCSTESYGREKSLKSVPSFEGSLSNSFVDSPRDSSYKPIATSTLKTESESGTSCKKWRLSFAQQRSSTLDDSKSDSISLPEVENISPVQHSLASSTDDSILYEENIFGAPTTPTCNLIAKEEFQTPISNLAANFSFNLCTPSITHVSDFEISVTEDSAFHSLSLDKSQDSITDHEGSFQELIQKPRVTPKAVHNKNRSRKLDRCRRLSTLRERGSQSEVEEEGNEAPLLSSAYKSKVARASVDEENEFSSDDSRVNSLLSIDDLTGKPALRVLHEMLLRSTRKRPQQATVQDLLGSSGCFELPEDSLSRLIGRKMGLVTFDILAELKYRNLKHIIASILGLMNVESICSMCRVSRDWRDIILQDKSAHQRRKAYMRRLKTEAEQGRQQSFEDSATTLNILSRSALKSVQIQARTAFQTPTSSLTPGDNKSIQSASKHQEYLQVAKTLFTDEALKPCPRCQFPAKYQALKKRGKCSRKDCGFDFCVLCLCTFHGSKECGTGSAKRIPKKEALPGSAQSKRNLKRL	Refseq >NP_001093338|F-box only protein 43 [Xenopus laevis] MANLLENFAAHHSMTAGAKKKADHQDTSVSQDSGYSDSLKGFSPDSHKSGNFLETVTEGYENSENIDPTLILSPIKYELSWGADTRESKQLAPLYETPRVGKKEFSLRRRLLISKATSGGNLDFDVSVCSAESCGREKSLRRIPSHEGSLSNSFADSPRDGSYEPIATSTLKTESESGTSCKKWRLSFAQQRSSTLDDSKSDSIPLPEVENISPVQHSLASSTDDSILYEETIFGAPTTPTCNFIVKEEFQTPISNLAANFRFNLCTPDVGHVSDFDISVTEDSAFHSLSLDKSQDSITDHEGSFQELIQKPRETSKAVNNKSRLRKLDRCRRLSTLRERGSQSEVEEEGNEVPVLSSAYKLKVARASVDEENEFSSDESRVHSLLSSDDLTGKPALRVLHEMLLRSTRKRPQQATVQDLLGSSGCFELPEDSLSRLIGRKMGLETFDILAELKNRNLKHILASILDLVNAASICSMCRVSRDWRDVVLQDKSAHQRRKAYIKKLKTEAEQGRQLSFEDSATRLNILSRSALRSVQIQARSAFRTPTSSLTPGDNKSIHSASKHQEYLKVAKTLFTDEALKPCPRCQYPAKYQALKKRGTCSRKDCGFDFCSLCLCTFHGSKECGTGSAKRIPKKEALPGSAQSKRNLKRL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.5514	Xl.76218
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		3 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	FBXO43
mouse		MGI	Fbxo43	All(1)
zebrafish

Publications
First:		Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity. [Genes Dev 2005]
Most recent:		The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles. [Biophys Chem 2013]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		calcium ion binding
Biological:
Cellular Component:
EC:
KOG:		[O] Predicted E3 ubiquitin ligase (alt_id KOG:1814)

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.52254.1.S1_at	Xl.3668.1.S1_at [+] Xl.16075.1.A1_at
Affymetrix 2.0			Xl2.3668.2.S1_at

Symbol legend[+]

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   - Literature Or Expression Images