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Summary Expression Gene Literature (56) GO Terms (42) Nucleotides (262) Proteins (53) Interactants (373) Wiki
XB-GENEPAGE-952024
Gene Symbol:
ptk2

Gene Name:
protein tyrosine kinase 2

Synonyms:
fak , pp125FAK , XPFAK ( Add synonyms , Nomenclature history )

Gene Function:
Focal adhesion tyrosine kinase FAK, contains FERM domain

Protein Function :
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin cluste...[+]


InterPro :
Kinase-like dom sf , Ubiquitin-like domsf , Focal adhesion kin target dom , FERM/acyl-CoA-bd prot sf [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-952025 XB-GENE-952029 XB-GENE-17337918
Gene Symbol ptk2 ptk2.L ptk2.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 733890
399286
432072
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ptk2 ptk2.L ptk2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PTK2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ptk2 MGI, IMPC Ensembl,