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Summary Expression Gene Literature (24) GO Terms (28) Nucleotides (160) Proteins (40) Interactants (863) Wiki
XB-GENEPAGE-952393

Gene Symbol: yap1

Gene Name: Yes associated protein 1

Synonyms: yap , yki , yap2 , yap65 , xyap ( Add synonyms , Nomenclature history )

Gene Function: Ubiquitin protein ligase RSP5/NEDD4

Protein Function :
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size c...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases: COLOBOMA, OCULAR, WITH OR WITHOUT HEARING IMPAIRMENT, CLEFT LIP/PALATE, AND/OR M

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Xenbase Gene ID XB-GENE-952394 XB-GENE-17333137 XB-GENE-952397
Gene Symbol yap1 yap1.L yap1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL RefSeq Swiss-Prot RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine yap1 yap1.L yap1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards YAP1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Yap1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR yap1 ZFIN Ensembl
chicken
GEISHA YAP1 Ensembl
fruit fly
worm
WORMBASE
Publications
First The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn., J Cell Biol 1998                    
Most Recent Linking YAP to Müller Glia Quiescence Exit in the Degenerative Retina., Cell Rep 2019      
All View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 28 terms 0 term 0 term
PANTHER yap1
KEGG Pathways K16687 K16687 K16687
KOG [O] Ubiquitin protein ligase RSP5/NEDD4
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Yap1 Ab1 , Yap1 Ab2 , Yap1 Ab3 , Yap1 Ab5 Yap1 Ab1 , Yap1 Ab2 , Yap1 Ab3 , Yap1 Ab4 , Yap1 Ab5
Morpholino yap1 MO1 , yap1 MO2 , yap1 MO3 , yap1 MO4 , yap1 MO5 , yap1 MO6 , yap1 MO7 yap1 MO1 , yap1 MO2 , yap1 MO3 , yap1 MO4 , yap1 MO5 , yap1 MO6 , yap1 MO7 yap1 MO1 , yap1 MO2 , yap1 MO3 , yap1 MO4 , yap1 MO5 , yap1 MO6 , yap1 MO7
ORF yap1.S ORF1
Affymetrix 1.0 Str.16747.2.S1_a_at Xl.16614.1.A1_at [+]
Affymetrix 2.0 Xl2.30038.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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