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Summary Expression Gene Literature (27) GO Terms (28) Nucleotides (183) Proteins (52) Interactants (871) Wiki
XB-GENEPAGE-952393
Gene Symbol:
yap1

Gene Name:
Yes associated protein 1

Synonyms:
yap , yki , yap2 , yap65 , xyap ( Add synonyms , Nomenclature history )

Gene Function:
Ubiquitin protein ligase RSP5/NEDD4

Protein Function :
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size c...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
uveal coloboma-cleft lip and palate-intellectual disability

OMIM:
COLOBOMA, OCULAR, WITH OR WITHOUT HEARING IMPAIRMENT, CLEFT LIP/PALATE, AND/OR M

External Links:
1/3
 
Xenbase Gene ID XB-GENE-952394 XB-GENE-17333137 XB-GENE-952397
Gene Symbol yap1 yap1.L yap1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100488779
100653494
100381098
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq Swiss-Prot RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine yap1 yap1.L yap1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards YAP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Yap1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Yap1 Ensembl
zebrafish
ZFIN, AGR yap1 ZFIN Ensembl
chicken
GEISHA YAP1 Ensembl
fruit fly
worm
Publications
First The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn., J Cell Biol 1998                    
Most Recent The transcription factor Hypermethylated in Cancer 1 (Hic1) regulates neural crest migration via interaction with Wnt signaling., Dev Biol 2020  
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 28 terms 2 terms 2 terms
PANTHER yap1
KEGG Pathways K16687 K16687 K16687
KOG [O] Ubiquitin protein ligase RSP5/NEDD4
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks yap1
Antibodies Yap1 Ab1 , Yap1 Ab2 , Yap1 Ab3 , Yap1 Ab5 Yap1 Ab1 , Yap1 Ab2 , Yap1 Ab3 , Yap1 Ab4 , Yap1 Ab5
Morpholinos yap1 MO1 , yap1 MO2 , yap1 MO3 , yap1 MO4 , yap1 MO5 , yap1 MO6 , yap1 MO7 yap1 MO1 , yap1 MO2 , yap1 MO3 , yap1 MO4 , yap1 MO5 , yap1 MO6 , yap1 MO7 yap1 MO1 , yap1 MO2 , yap1 MO3 , yap1 MO4 , yap1 MO5 , yap1 MO6 , yap1 MO7
ORFs yap1.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

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