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Summary Expression Gene Literature (18) GO Terms (16) Nucleotides (148) Proteins (29) Interactants (467) Wiki
XB-GENEPAGE- 952393

Gene Symbol: yap1

Gene Name: Yes associated protein 1

Synonyms: yap , yki , yap2 , yap65 , xyap
Add Xenopus synonyms , Nomenclature history


Gene Function: Ubiquitin protein ligase RSP5/NEDD4

Protein Function:
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size c...[+]


Interactants: YYY

OMIM Disease Associations: COLOBOMA, OCULAR, WITH OR WITHOUT HEARING IMPAIRMENT, CLEFT ...
1/3
 
Xenbase Gene ID XB-GENE-952394 XB-GENE-17333137 XB-GENE-952397
Gene Symbol yap1 yap1.L yap1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot Swiss-Prot Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.16747 Xl.30038 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 10 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine yap1 yap1.L yap1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards YAP1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Yap1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN yap1 ZFIN Ensembl
chicken
GEISHA YAP1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn. [J Cell Biol 1998]
Most recent: Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates. [Dev Biol 2017]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 4 terms 4 terms
EC
PANTHER yap1
KEGG Pathways K16687 K16687 K16687
KOG [O] Ubiquitin protein ligase RSP5/NEDD4
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Yap1 Ab1 , Yap1 Ab2 , Yap1 Ab3 , Yap1 Ab5 Yap1 Ab1 , Yap1 Ab2 , Yap1 Ab3 , Yap1 Ab4 , Yap1 Ab5
Morpholino yap1 MO1 , yap1 MO2 , yap1 MO3 , yap1 MO4 , yap1 MO5 , yap1 MO6 , yap1 MO7 yap1 MO1 , yap1 MO2 , yap1 MO3 , yap1 MO4 , yap1 MO5 , yap1 MO6 , yap1 MO7 yap1 MO1 , yap1 MO2 , yap1 MO3 , yap1 MO4 , yap1 MO5 , yap1 MO6 , yap1 MO7
ORF yap1 ORF1
Affymetrix 1.0 Str.16747.2.S1_a_at Xl.16614.1.A1_at [+]
Affymetrix 2.0 Xl2.30038.1.S1_at [+]

Symbol legend[+]

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