Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (54) GO Terms (21) Nucleotides (114) Proteins (37) Interactants (956) Wiki
XB-GENEPAGE-953989
Gene Symbol:
mcc

Gene Name:
mutated in colorectal cancers

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Uncharacterized conserved coiled-coil protein

Protein Function :
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone...[+]


InterPro :
EF hand dom , EF-hand-dom pair , EF Hand 1 Ca BS , USBP1-like [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-953990 XB-GENE-17332747 XB-GENE-17332748
Gene Symbol mcc mcc.L mcc.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 100216150
108707212
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine mcc mcc.L mcc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MCC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mcc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mcc Ensembl
zebrafish
mcc Ensembl
chicken
GEISHA MCC Ensembl
fruit fly
worm
Publications
First Large-scale purification of the vertebrate anaphase-promoting complex/cyclosome., Methods Enzymol 2005  
Most Recent Conservation as well as divergence in Mcidas function underlies the differentiation of multiciliated cells in vertebrates., Dev Biol 2020  
All View All Papers 13 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 16 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 0 term 0 term
PANTHER mcc
KEGG Pathways
KOG [S] Uncharacterized conserved coiled-coil protein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks mcc
Morpholinos mcc MO1 mcc MO1 mcc MO1
Clones Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.16.0
Major funding for Xenbase is provided by grant P41 HD064556