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Summary Expression Gene Literature (11) GO Terms (3) Nucleotides (199) Proteins (26) Interactants (189) Wiki
XB-GENEPAGE- 954260

Gene Symbol: ldlrap1

Gene Name: low density lipoprotein receptor adaptor protein 1

Synonyms: arh , arh1 , arh2 , fhcb1 , fhcb2 , xptb , ldlrap1-a , ldlrap1-b
Add Xenopus synonyms , Nomenclature history


Gene Function: Adaptor protein CED-6, contains PTB domain

Protein Function:
Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR). Also involved in the vitellogenin receptor mediated endocytosis of nutrients...[+]


Interactants: YYY

OMIM Disease Associations: HYPERCHOLESTEROLEMIA, AUTOSOMAL RECESSIVE; ARH
 
Xenbase Gene ID XB-GENE-954261 XB-GENE-6256035 XB-GENE-954266
Gene Symbol ldlrap1 ldlrap1.L ldlrap1.S
Chromosome scaffold_2 Scaffold166674 Scaffold47026
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 7.2 JBrowse 7.2
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v7.2 gene model
GBrowse
laevis genome v7.2 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene [+] Xl.13266 Xl.8355 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 6 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine ldlrap1 ldlrap1.L ldlrap1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LDLRAP1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Ldlrap1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN ldlrap1b ldlrap1a ZFIN Ensembl
chicken
GEISHA LDLRAP1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2. [J Biol Chem 2002]
Most recent: High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration. [Development 2017]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 3 terms 3 terms
EC
PANTHER ldlrap1
KEGG Pathways K12474 K12474 K12474
KOG [R] Adaptor protein CED-6, contains PTB domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Ldlrap1 Ab1 Ldlrap1 Ab1 Ldlrap1 Ab1
ORF ldlrap1 ORF1
Affymetrix 1.0 Str.11033.1.S1_at [+] Xl.13266.1.S1_at Xl.8355.1.S1_at [+]
Affymetrix 2.0 Xl2.13266.1.S1_a_at Xl2.8355.1.S1_at [+]

Symbol legend[+]

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