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Summary Expression Gene Literature (2) GO Terms (26) Nucleotides (149) Proteins (36) Interactants (210) Wiki
XB-GENEPAGE-955051
Gene Symbol:
ndst1

Gene Name:
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Heparan sulfate N-deacetylase/N-sulfotransferase

Protein Function :
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repe...[+]



Interactants:
Loading ...

Diseases: 


OMIM:
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 46; MRT46

External Links:
 
Xenbase Gene ID XB-GENE-955052 XB-GENE-17339671 XB-GENE-955057
Gene Symbol ndst1 ndst1.L ndst1.S
Chromosome Chr03 chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 496577
443855
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine ndst1 ndst1.L ndst1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards NDST1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ndst1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ndst1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR ndst1a ndst1b ZFIN Ensembl
chicken
GEISHA NDST1 Ensembl
fruit fly
worm
Publications
First Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus., Nat Commun 2017                                                    
Most Recent High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Dev Biol 2017                    
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 26 terms 0 term 6 terms
PANTHER ndst1
KEGG Pathways K02576 K02576
KOG [O] Heparan sulfate N-deacetylase/N-sulfotransferase
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ndst1
Morpholinos ndst1 MO1 , ndst1 MO2 ndst1 MO1 , ndst1 MO2 ndst1 MO1 , ndst1 MO2
Clones Horizon Source BioScience Horizon

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