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Summary Expression Gene Literature (12) GO Terms (18) Nucleotides (143) Proteins (44) Interactants (227) Wiki
XB-GENEPAGE-955451
Gene Symbol:
tbk1

Gene Name:
TANK binding kinase 1

Synonyms:
nak , t2k ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by viral or bacterial components, associates wit...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
frontotemporal dementia and/or amyotrophic lateral sclerosis-4

OMIM:
ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8 [+]

External Links:
 
Xenbase Gene ID XB-GENE-955452 XB-GENE-955455 XB-GENE-17336009
Gene Symbol tbk1 tbk1.L tbk1.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100216212
446351
108712371
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tbk1 tbk1.L tbk1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TBK1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tbk1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tbk1 Ensembl
zebrafish
ZFIN, AGR tbk1 ZFIN Ensembl
chicken
GEISHA TBK1 Ensembl
fruit fly
worm
Publications
First The H,K-ATPase beta-subunit can act as a surrogate for the beta-subunit of Na,K-pumps., J Biol Chem 1991  
Most Recent The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development., Sci Rep 2018                                      
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 8 terms 0 term
PANTHER tbk1
KEGG Pathways K05410 K05410
KOG [T] TANK binding protein kinase TBK1
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tbk1
ORFs tbk1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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