Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (18) GO Terms (16) Nucleotides (383) Proteins (49) Interactants (99) Wiki
XB-GENEPAGE-955682
Gene Symbol:
bub3

Gene Name:
BUB3 mitotic checkpoint protein

Synonyms:
xbub3 ( Add synonyms , Nomenclature history )

Gene Function:
Mitotic spindle checkpoint protein BUB3, Wrepeat superfamily

Protein Function :
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Plays a role in the kinetochore-mediated mitotic c...[+]



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-955683 XB-GENE-955689 XB-GENE-17344137
Gene Symbol bub3 bub3.L bub3.S
Chromosome Chr07 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 493224
399106
108697375
mRNA RefSeq RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine bub3 bub3.L bub3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BUB3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Bub3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Bub3 Ensembl
zebrafish
ZFIN, AGR bub3 ZFIN Ensembl
chicken
GEISHA BUB3 Ensembl
fruit fly
FLYBASE Bub3 Ensembl
worm
Publications
First Maternal transcripts of mitotic checkpoint gene, Xbub3, are accumulated in the animal blastomeres of Xenopus early embryo., DNA Cell Biol 1999  
Most Recent A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling., Elife 2017                
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 5 terms 0 term
PANTHER bub3
KEGG Pathways K02180 K02180 K02180
KOG [D] Mitotic spindle checkpoint protein BUB3, Wrepeat superfamily
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks bub3
ORFs bub3 ORF1 bub3.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556