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Summary Expression Gene Literature (74) GO Terms (5) Nucleotides (348) Proteins (26) Interactants (88) Wiki
XB-GENEPAGE- 955797

Gene Symbol: gjb2

Gene Name: gap junction protein beta 2

Synonyms: cx26 , connexin-26 , connexin 26 , dfna3 , dfna3a , dfnb1 , dfnb1a , nsrd1 , ppk , cx29
Add Xenopus synonyms , Nomenclature history


Gene Function: connexon channel component

Protein Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.


Interactants: Loading ...

OMIM Disease Associations: DEAFNESS, AUTOSOMAL DOMINANT 3A; DFNA3A [+]
 
Xenbase Gene ID XB-GENE-955798 XB-GENE-955804 XB-GENE-17336902
Gene Symbol gjb2 gjb2.L gjb2.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.6148 [+] Xl.8924 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 7 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine gjb2 gjb2.L gjb2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GJB2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Gjb2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
cx31.7 ZFIN Ensembl
chicken
GEISHA GJB2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Molecular cloning and characterization of a new member of the gap junction gene family, connexin-31. [J Biol Chem 1991]
Most recent: Charged Residues at the First Transmembrane Region Contribute to the Voltage Dependence of the Slow Gate of Connexins. [J Biol Chem 2016]
View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 3 terms 0 term
EC
PANTHER gjb2
KEGG Pathways K07621 [+] K07625
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF gjb2 ORF1
Affymetrix 1.0 Str.6148.1.S1_at Xl.8924.1.A1_at
Affymetrix 2.0 Xl2.8924.1.S1_s_at

Symbol legend[+]

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