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Summary Expression Gene Literature (24) GO Terms (7) Nucleotides (304) Proteins (41) Interactants (791) Wiki
XB-GENEPAGE-956214

Gene Symbol: ezh2

Gene Name: enhancer of zeste 2 polycomb repressive complex 2 subunit

Synonyms: enx1 , ezh1 , kmt6 , enx-1 , xez , xtezh2 , ezh2-a , ezh2-b ( Add Xenopus synonyms , Nomenclature history )

Gene Function: Transcriptional repressor EZH1

Protein Function :
Polycomb group (PcG) protein. Catalytic subunit of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. May...[+]

Interactants: Loading ...
Disease Ontology: WEAVER SYNDROME

OMIM Diseases: WEAVER SYNDROME; WVS
1/8
 
Xenbase Gene ID XB-GENE-956215 XB-GENE-956220 XB-GENE-6252001
Gene Symbol ezh2 ezh2.L ezh2.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Swiss-Prot Refseq Swiss-Prot TrEMBL Swiss-Prot Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images                   Ensembl In situ: Single cell: RNA-Seq:  
Data Mining tropicalis laevis.L laevis.S
XenMine ezh2 ezh2.L ezh2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards EZH2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ezh2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ezh2 ZFIN Ensembl
chicken
GEISHA EZH2 Ensembl
fruit fly
worm
WORMBASE
Publications
First The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos., Mol Cell Biol 2001  
Most recent Xenopus SOX5 enhances myogenic transcription indirectly through transrepression., Dev Biol 2018                      
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 7 terms 7 terms
PANTHER ezh2
KEGG Pathways K11430 K11430 K11430
KOG [K] Transcriptional repressor EZH1
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Antibody Ezh2 Ab1 Ezh2 Ab1 Ezh2 Ab1
Morpholino ezh2 MO1 , ezh2 MO2 ezh2 MO1 , ezh2 MO2 ezh2 MO1 , ezh2 MO2
ORF ezh2.S ORF1
Affymetrix 1.0 StrJgi.3836.1.S1_at [+] Xl.19136.1.S1_at
Affymetrix 2.0 Xl2.19136.1.S1_a_at [+] Xl2.47646.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.10.0


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