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XB-GENEPAGE-956236
Gene Symbol:
kbtbd8
Gene Name: kelch repeat and BTB (POZ) domain containing 8
Synonyms:
( Gene Function: Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes Protein Function
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Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (PubMed:26399832). The BCR(KBTBD8) complex acts by mediating monou...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-956237 | XB-GENE-17336198 | XB-GENE-6488371 | |||||
Gene Symbol | kbtbd8 | kbtbd8.L | kbtbd8.S | Chromosome | Chr4 | chr4L | chr4S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100492015
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108714728
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108715925
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | kbtbd8 | kbtbd8.L | kbtbd8.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Cell-fate determination by ubiquitin-dependent regulation of translation., Nature 2015 ![]() |
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Most Recent |
Dimerization quality control ensures neuronal development and survival., Science 2018 |
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All | View All Papers | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 7 terms | 3 terms | 3 terms | |||||
PANTHER | kbtbd8 | |||||||
KEGG Pathways | K10475 | K10475 | ||||||
KOG |
[TR] Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | kbtbd8 | |||||||
Morpholinos (on-target & off-target) | kbtbd8 MO1 , kbtbd8 MO2 , kbtbd8 MO3 | kbtbd8 MO1 , kbtbd8 MO3 | kbtbd8 MO1 , kbtbd8 MO3 | |||||
Clones | Horizon Source BioScience | Horizon | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
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