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Summary Expression Gene Literature (2) GO Terms (7) Nucleotides (80) Proteins (35) Interactants (25) Wiki
XB-GENEPAGE-956236
Gene Symbol:
kbtbd8

Gene Name:
kelch repeat and BTB (POZ) domain containing 8

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes

Protein Function :
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (PubMed:26399832). The BCR(KBTBD8) complex acts by mediating monou...[+]


InterPro :
BTB/POZ dom , BTB-kelch protein , Kelch 1 , SKP1/BTB/POZ sf [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-956237 XB-GENE-17336198 XB-GENE-6488371
Gene Symbol kbtbd8 kbtbd8.L kbtbd8.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100492015
108714728
108715925
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine kbtbd8 kbtbd8.L kbtbd8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KBTBD8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kbtbd8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kbtbd8 Ensembl
zebrafish
ZFIN, AGR kbtbd8 ZFIN Ensembl
chicken
GEISHA KBTBD8 Ensembl
fruit fly
worm
Publications
First Cell-fate determination by ubiquitin-dependent regulation of translation., Nature 2015                              
Most Recent Dimerization quality control ensures neuronal development and survival., Science 2018  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 7 terms 3 terms 3 terms
PANTHER kbtbd8
KEGG Pathways K10475 K10475
KOG [TR] Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks kbtbd8
Morpholinos (on-target & off-target) kbtbd8 MO1 , kbtbd8 MO2 , kbtbd8 MO3 kbtbd8 MO1 , kbtbd8 MO3 kbtbd8 MO1 , kbtbd8 MO3
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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