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Summary Expression Gene Literature (23) GO Terms (22) Nucleotides (246) Proteins (37) Interactants (328) Wiki
XB-GENEPAGE-956981
Gene Symbol:
wls

Gene Name:
wntless Wnt ligand secretion mediator

Synonyms:
wntless , evi , mrp , gpr177 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Required for a subset of Wnt-dependent developmental processes, in particular, eye and pronephros development. Regulates the secretion of wnt4, which is required for eye development.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-956982 XB-GENE-956987 XB-GENE-6253761
Gene Symbol wls wls.L wls.S
Chromosome Chr04 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549664
735023
447540
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine wls wls.L wls.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards WLS OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Wls MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Wls Ensembl
zebrafish
ZFIN, AGR wls ZFIN Ensembl
chicken
GEISHA WLS Ensembl
fruit fly
FLYBASE wls Ensembl
worm
Publications
First Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines., Cell 1988  
Most Recent eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled., J Biol Chem 2020            
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 9 terms 8 terms
PANTHER wls
KEGG Pathways
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks wls
Morpholinos wls MO1 wls MO1 wls MO1
ORFs wls.L ORF1 wls.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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