Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (7) GO Terms (11) Nucleotides (209) Proteins (42) Interactants (530) Wiki
XB-GENEPAGE-957709
Gene Symbol:
pfkfb1

Gene Name:
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Fructose-6-phosphate 2-kinase/fructose-2,6-biphosphatase

Protein Function :
Synthesis and degradation of fructose 2,6-bisphosphate.


InterPro :
SP NH2Trfase/AEP transaminase , PyrdxlP-dep Trfase , PyrdxlP-dep Trfase major , Aminotrans V PyrdxlP BS [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/7
 
Xenbase Gene ID XB-GENE-957710 XB-GENE-17337971 XB-GENE-957713
Gene Symbol pfkfb1 pfkfb1.L pfkfb1.S
Chromosome Chr8 chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100488795
495408
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pfkfb1 pfkfb1.L pfkfb1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards PFKFB1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pfkfb1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pfkfb1 Ensembl
zebrafish
ZFIN, AGR pfkfb1 ZFIN Ensembl
chicken
GEISHA GEISHA PFKFB1 PFKFB1 Ensembl
fruit fly
Publications
First Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning., Mech Dev 1998                                                              
Most Recent Phosphoproteomic Analysis of Xenopus laevis Reveals Expression and Phosphorylation of Hypoxia-Inducible PFKFB3 during Dehydration., iScience 2020                  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 0 term 5 terms
PANTHER pfkfb1
KEGG Pathways K19028 K19028
KOG [G] Fructose-6-phosphate 2-kinase/fructose-2,6-biphosphatase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pfkfb1
ORFs pfkfb1.S ORF1
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info