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XB-GENEPAGE-957955
Gene Symbol:
mre11
Gene Name: MRE11 homolog , double strand break repair nuclease
Synonyms:
mre11a
( Gene Function: DNA repair exonuclease MRE11 Protein Function
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Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
Interactants:
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Diseases: OMIM:
ATAXIA-TELANGIECTASIA-LIKE DISORDER 1; ATLD1
External Links:
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Xenbase Gene ID
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XB-GENE-957956 | XB-GENE-957959 | XB-GENE-17332692 | |||||
Gene Symbol | mre11 | mre11.L | mre11.S | Chromosome | Chr2 | chr2L | ||
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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CDS |
Gene model
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Gene model
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Entrez Gene |
100135381
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394308
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | mre11 | mre11.L | mre11.S | |||||
Orthology ![]() |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication., Mol Cell 2001 |
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Most Recent |
Conservation and divergence of protein pathways in the vertebrate heart., PLoS Biol 2019 ![]() |
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All | View All Papers 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 26 terms | 11 terms | 0 term | |||||
PANTHER | mre11 | |||||||
KEGG Pathways | K10865 | K10865 | ||||||
KOG |
[L] DNA repair exonuclease MRE11
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | mre11 | |||||||
Antibodies | Mre11a Ab1 | Mre11a Ab1 | Mre11a Ab1 | |||||
ORFs | mre11.L ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | ||||||
Plasmids | Addgene | Addgene |
Symbol legend:



