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XB-GENEPAGE-960721
Gene Symbol:
mc4r
Gene Name: melanocortin 4 receptor
Synonyms:
( Gene Function: Glycoprotein hormone receptor Protein Function
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Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediat...[+]
Interactants:
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Diseases: Disease Ontology:
obesity
OMIM:
OBESITY
External Links:
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Xenbase Gene ID
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XB-GENE-960722 | XB-GENE-17343871 | XB-GENE-17343872 | |||||
Gene Symbol | mc4r | mc4r.L | mc4r.S | Chromosome | Chr6 | chr6L | chr6S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100486677
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108719094
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108695258
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | mc4r | mc4r.L | mc4r.S | |||||
Orthology ![]() |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein., Science 1997 |
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Most Recent |
Pharmacological modulation of dual melanocortin-4 receptor signaling by melanocortin receptor accessory proteins in the Xenopus laevis., J Cell Physiol 2021 |
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All | View All Papers 1 paper(s) referencing OMIMs | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 0 term | 3 terms | 3 terms | |||||
PANTHER | mc4r | |||||||
KEGG Pathways | K04202 | K04202 | ||||||
KOG |
[T] Glycoprotein hormone receptor
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | mc4r | |||||||
Morpholinos | mc4r MO2 | |||||||
Clones | Horizon | Horizon | Horizon | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



