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Summary Expression Gene Literature (5) GO Terms (14) Nucleotides (51) Proteins (23) Interactants (86) Wiki
XB-GENEPAGE-960778
Gene Symbol:
cyp11a1

Gene Name:
cytochrome P450 family 11 subfamily A member 1

Synonyms:
p450scc ( Add synonyms , Nomenclature history )

Gene Function:
Cytochrome P450 CYP11/CYP12/CYP24/CYP27 subfamilies

Protein Function :
A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation rea...[+]



Interactants:
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Diseases: 


Disease Ontology:
congenital adrenal hyperplasia

OMIM:
LIPOID CONGENITAL ADRENAL HYPERPLASIA; LCAH [+]

External Links:
 
Xenbase Gene ID XB-GENE-960779 XB-GENE-17340215 XB-GENE-6487482
Gene Symbol cyp11a1 cyp11a1.L cyp11a1.S
Chromosome Chr03 chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100495360
108712986
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine cyp11a1 cyp11a1.L cyp11a1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CYP11A1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cyp11a1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cyp11a1 Ensembl
zebrafish
ZFIN, AGR cyp11a1 ZFIN Ensembl
chicken
GEISHA CYP11A1 Ensembl
fruit fly
worm
Publications
First Pregnenolone, pregnenolone sulfate, and cytochrome P450 side-chain cleavage enzyme in the amphibian brain and their seasonal changes., Endocrinology 1999  
Most Recent Identification and characterization of Xenopus tropicalis common progenitors of Sertoli and peritubular myoid cell lineages., Biol Open 2016            
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 0 term 8 terms
PANTHER cyp11a1
KEGG Pathways K00498 K00498
KOG [Q] Cytochrome P450 CYP11/CYP12/CYP24/CYP27 subfamilies
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks cyp11a1
Clones Horizon Horizon Source BioScience

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