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Summary Expression Gene Literature (87) GO Terms (15) Nucleotides (116) Proteins (33) Interactants (211) Wiki
XB-GENEPAGE-963584
Gene Symbol:
ism1

Gene Name:
isthmin 1, angiogenesis inhibitor

Synonyms:
isthmin ( Add synonyms , Nomenclature history )

Gene Function:
Immunoglobin and related proteins

Protein Function :
May act as an angiogenesis inhibitor.



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-963585 XB-GENE-963588 XB-GENE-17343480
Gene Symbol ism1 ism1.L ism1.S
Chromosome Chr5 chr5L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100487287
398306
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ism1 ism1.L ism1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ISM1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ism1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ism1 Ensembl
zebrafish
ZFIN, AGR ism1 ZFIN Ensembl
chicken
GEISHA ISM1 Ensembl
fruit fly
worm
Publications
First Isthmin is a novel secreted protein expressed as part of the Fgf-8 synexpression group in the Xenopus midbrain-hindbrain organizer., Mech Dev 2002        
Most Recent ISM1 regulates NODAL signaling and asymmetric organ morphogenesis during development., J Cell Biol 2019                    
All View All Papers 3 paper(s) referencing morpholinos 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 1 terms 0 term
PANTHER ism1
KEGG Pathways
KOG [RP] FOG: Immunoglobin and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ism1
Morpholinos ism1 MO1 , ism1 MO2 ism1 MO1 , ism1 MO2 ism1 MO1 , ism1 MO2
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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