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XB-GENEPAGE-964547
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Gene Symbol: mastl
Gene Name: microtubule associated serine/threonine kinase like Synonyms: greatwall , gwl , mast-l , thc2 , gw ( Add Xenopus synonyms , Nomenclature history ) Gene Function: cAMP-dependent protein kinase catalytic subunit (PKA) Protein Function  :
Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: d...[+]
Interactants: Loading ... 
Disease Ontology: THROMBOCYTOPENIA OMIM Diseases: THROMBOCYTOPENIA 2; THC2 |
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| Xenbase Gene ID | XB-GENE-964548 | XB-GENE-964551 | XB-GENE-17339965 | ||||
| Gene Symbol | mastl | mastl.L | mastl.S | ||||
| Chromosome | Chr06 | Scaffold17434 | |||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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| Protein
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Refseq
Swiss-Prot
TrEMBL
Swiss-Prot
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Refseq
Swiss-Prot
Swiss-Prot
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
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| Genomic Synteny | Genomicus PANTHER | ||||||
| Expression | Development Stages | Embryonic Tissues | Adult Tissues | ||||
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| More Information |
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| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | mastl | mastl.L | mastl.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| zebrafish |
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| Publications | |||||||
| First | Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts., Mol Cell 2006 | ||||||
| Most recent | The greatwall kinase is dominant over PKA in controlling the antagonistic function of ARPP19 in Xenopus oocytes., Cell Cycle 2017 | ||||||
| All | View All Papers | ||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 16 terms | 16 terms | 0 term | ||||
| PANTHER | mastl | ||||||
| KEGG Pathways | K16309 | K16309 | |||||
| KOG |
[T] cAMP-dependent protein kinase catalytic subunit (PKA)
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
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| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Antibody | Mastl Ab1 , Mastl Ab2 | Mastl Ab1 , Mastl Ab2 | |||||
| ORF | mastl.L ORF1 | ||||||
| Affymetrix 1.0 | Str.3977.1.S1_at | Xl.3201.1.A1_at | |||||
| Affymetrix 2.0 | Xl2.3201.1.S1_at | ||||||
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