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Summary Expression Gene Literature (44) GO Terms (18) Nucleotides (146) Proteins (31) Interactants (178) Wiki
XB-GENEPAGE-964547

Gene Symbol: mastl

Gene Name: microtubule associated serine/threonine kinase like

Synonyms: greatwall , gwl , mast-l , thc2 , gw ( Add Xenopus synonyms , Nomenclature history )

Gene Function: cAMP-dependent protein kinase catalytic subunit (PKA)

Protein Function :
Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: d...[+]

Interactants: Loading ...
Disease Ontology: THROMBOCYTOPENIA

OMIM Diseases: THROMBOCYTOPENIA 2; THC2
 
Xenbase Gene ID XB-GENE-964548 XB-GENE-964551 XB-GENE-17339965
Gene Symbol mastl mastl.L mastl.S
Chromosome Chr06 Scaffold17434
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Swiss-Prot Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images                   Ensembl In situ: Single cell: RNA-Seq:  
Data Mining tropicalis laevis.L laevis.S
XenMine mastl mastl.L mastl.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MASTL OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Mastl MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR mastl ZFIN Ensembl
chicken
GEISHA MASTL Ensembl
fruit fly
worm
WORMBASE
Publications
First Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts., Mol Cell 2006  
Most recent The greatwall kinase is dominant over PKA in controlling the antagonistic function of ARPP19 in Xenopus oocytes., Cell Cycle 2017  
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 16 terms 0 term
PANTHER mastl
KEGG Pathways K16309 K16309
KOG [T] cAMP-dependent protein kinase catalytic subunit (PKA)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Antibody Mastl Ab1 , Mastl Ab2 Mastl Ab1 , Mastl Ab2
ORF mastl.L ORF1
Affymetrix 1.0 Str.3977.1.S1_at Xl.3201.1.A1_at
Affymetrix 2.0 Xl2.3201.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.10.0


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