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XB-GENEPAGE-964547
Gene Symbol:
mastl
Gene Name: microtubule associated serine/threonine kinase like
Synonyms:
greatwall
,
gwl
,
mast-l
,
thc2
,
gw
( Gene Function: cAMP-dependent protein kinase catalytic subunit (PKA) Protein Function
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Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: d...[+]
Interactants:
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Diseases: Disease Ontology:
thrombocytopenia
OMIM:
THROMBOCYTOPENIA 2; THC2
External Links:
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Xenbase Gene ID | XB-GENE-964548 | XB-GENE-964551 | XB-GENE-17339965 | |||||
Gene Symbol | mastl | mastl.L | mastl.S | Chromosome | Chr6 | chr6L | ||
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.2
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CDS |
Gene model
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Gene model
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Entrez Gene |
100145700
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414585
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | mastl | mastl.L | mastl.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts., Mol Cell 2006 |
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Most Recent |
Bistable, Biphasic Regulation of PP2A-B55 Accounts for the Dynamics of Mitotic Substrate Phosphorylation., Curr Biol 2020 ![]() |
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All | View All Papers | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 20 terms | 14 terms | 0 term | |||||
PANTHER | mastl | |||||||
KEGG Pathways | K16309 | K16309 | ||||||
KOG |
[T] cAMP-dependent protein kinase catalytic subunit (PKA)
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | mastl | |||||||
Antibodies | Mastl Ab1 , Mastl Ab2 | Mastl Ab1 , Mastl Ab2 | ||||||
ORFs | mastl.L ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | ||||||
Plasmids | Addgene | Addgene |
Symbol legend:



