|
XB-GENEPAGE-
964547
|
Gene Symbol: mastl
Gene Name: microtubule associated serine/threonine kinase like Synonyms: greatwall , gwl , mast-l , thc2 , gw Add Xenopus synonyms , Nomenclature history Gene Function: cAMP-dependent protein kinase catalytic subunit (PKA) Protein Function  :
Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: d...[+]
Interactants: Loading ... 
Disease Ontology: THROMBOCYTOPENIA OMIM Diseases: THROMBOCYTOPENIA 2; THC2 |
|
| Xenbase Gene ID | XB-GENE-964548 | XB-GENE-964551 | XB-GENE-17339965 | ||||
| Gene Symbol | mastl | mastl.L | mastl.S | ||||
| Chromosome | Chr06 | Scaffold17434 | |||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
|
||||||
| CDS |
Gene model
|
||||||
|
Entrez Gene
|
Entrez Gene
|
||||||
| mRNA |
Refseq
|
Refseq
|
|||||
| Protein
|
Refseq
Swiss-Prot
TrEMBL
|
Refseq
Swiss-Prot
|
|||||
| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser | |||||||
| Links |
|
||||||
| Genomic Synteny | Genomicus PANTHER | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.3977 | Xl.3201 | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
|
|||||
| Experimental regulation |
Regulation heatmap:
|
||||||
| Images | 0 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | mastl | mastl.L | mastl.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
|
||||||
| human |
|
||||||
| mouse |
|
||||||
| zebrafish |
|
||||||
| chicken |
|
||||||
| fruit fly |
|
||||||
| worm |
|
||||||
| Publications | |||||||
| First: | Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts. [Mol Cell 2006] | ||||||
| Most recent: | The greatwall kinase is dominant over PKA in controlling the antagonistic function of ARPP19 in Xenopus oocytes. [Cell Cycle 2017] | ||||||
| View All Papers | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 16 terms | 16 terms | 0 term | ||||
| PANTHER | mastl | ||||||
| KEGG Pathways | K16309 | K16309 | |||||
| KOG |
[T] cAMP-dependent protein kinase catalytic subunit (PKA)
|
||||||
| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | |||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Antibody | Mastl Ab1 , Mastl Ab2 | Mastl Ab1 , Mastl Ab2 | |||||
| ORF | mastl.L ORF1 | ||||||
| Affymetrix 1.0 | Str.3977.1.S1_at | Xl.3201.1.A1_at | |||||
| Affymetrix 2.0 | Xl2.3201.1.S1_at | ||||||
Symbol legend[+]
- Literature Or Expression Images
