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Summary Expression Gene Literature (37) GO Terms (38) Nucleotides (448) Proteins (42) Interactants (374) Wiki
XB-GENEPAGE-965561
Gene Symbol:
dnmt1

Gene Name:
DNA methyltransferase 1

Synonyms:
xDnmt1 , DNA MeTase ( Add synonyms , Nomenclature history )

Gene Function:
maintenance methyltransferase

Protein Function :


InterPro :
ETS V1 , WH DNA-bd sf , Ets dom , WH-like DNA-bd sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
autosomal dominant cerebellar ataxia, deafness and narcolepsy [+]

OMIM:
CEREBELLAR ATAXIA, DEAFNESS, AND NARCOLEPSY, AUTOSOMAL DOMINANT; ADCADN [+]

External Links:
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Xenbase Gene ID XB-GENE-965562 XB-GENE-965566 XB-GENE-17332488
Gene Symbol dnmt1 dnmt1.L dnmt1.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100151716
399257
100036795
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dnmt1 dnmt1.L dnmt1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards DNMT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
rat
RGD, AGR Dnmt1 Ensembl
zebrafish
chicken
GEISHA DNMT1 Ensembl
fruit fly
Publications
First Transient depletion of xDnmt1 leads to premature gene activation in Xenopus embryos., Genes Dev 2000                      
Most Recent Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals., Nat Commun 2020                  
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 38 terms 5 terms 5 terms
PANTHER dnmt1
KEGG Pathways K00558 K00558 K00558
KOG [K] Transcription factor TCF20
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dnmt1
Antibodies Dnmt1 Ab2 , Dnmt1 Ab1 , Dnmt1 Ab3 Dnmt1 Ab2 , Dnmt1 Ab1 , Dnmt1 Ab3 Dnmt1 Ab3
Morpholinos dnmt1 MO1 dnmt1 MO2
ORFs dnmt1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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