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Summary Expression Gene Literature (138) GO Terms (42) Nucleotides (1302) Proteins (59) Interactants (931) Wiki
XB-GENEPAGE-967584
Gene Symbol:
cdc42

Gene Name:
cell division cycle 42

Synonyms:
Xcdc42 ( Add synonyms , Nomenclature history )

Gene Function:
small GTPase

Protein Function :
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.


InterPro :
Kinase-like dom sf , Ser/Thr kinase AS , Prot kinase dom , MRCKB STKc [+]

Interactants:
Loading ...

Diseases: 


OMIM:
TAKENOUCHI-KOSAKI SYNDROME; TKS

External Links:
1/5
 
Xenbase Gene ID XB-GENE-967585 XB-GENE-6251832 XB-GENE-17339258
Gene Symbol cdc42 cdc42.L cdc42.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493389
379055
108697660
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cdc42 cdc42.L cdc42.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tgas029e03      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards CDC42 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cdc42 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cdc42 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR cdc42 cdc42l ZFIN Ensembl
chicken
GEISHA CDC42 Ensembl
fruit fly
FLYBASE Cdc42 Ensembl
Publications
First A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos., Curr Biol 1997  
Most Recent DAAM2 Variants Cause Nephrotic Syndrome via Actin Dysregulation., Am J Hum Genet 2020  
All View All Papers 15 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 42 terms 7 terms 5 terms
PANTHER cdc42
KEGG Pathways K04393 K04393 K04393
KOG [R] Ras-related small GTPase, Rho type
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cdc42
Antibodies Cdc42 Ab1 Cdc42 Ab1
Morpholinos cdc42 MO1 cdc42 MO1 cdc42 MO1
ORFs cdc42 ORF2 cdc42.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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