Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (134) GO Terms (41) Nucleotides (1296) Proteins (52) Interactants (914) Wiki
XB-GENEPAGE-967584
Gene Symbol:
cdc42

Gene Name:
cell division cycle 42

Synonyms:
Xcdc42 ( Add synonyms , Nomenclature history )

Gene Function:
small GTPase

Protein Function :


InterPro :
Kinase-like dom sf , Ser/Thr kinase AS , Prot kinase dom , MRCKB STKc [+]

Interactants:
Loading ...

Diseases: 


OMIM:
TAKENOUCHI-KOSAKI SYNDROME; TKS

External Links:
1/5
 
Xenbase Gene ID XB-GENE-967585 XB-GENE-6251832 XB-GENE-17339258
Gene Symbol cdc42 cdc42.L cdc42.S
Chromosome Chr07 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 493389
379055
108697660
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cdc42 cdc42.L cdc42.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tgas029e03      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CDC42 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cdc42 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cdc42 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR cdc42 cdc42l ZFIN Ensembl
chicken
GEISHA CDC42 Ensembl
fruit fly
FLYBASE Cdc42 Ensembl
worm
Publications
First A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos., Curr Biol 1997  
Most Recent Dynamics of actin polymerisation during the mammalian single-cell wound healing response., BMC Res Notes 2019        
All View All Papers 15 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 41 terms 5 terms 3 terms
PANTHER cdc42
KEGG Pathways K04393 K04393 K04393
KOG [R] Ras-related small GTPase, Rho type
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cdc42
Antibodies Cdc42 Ab1 Cdc42 Ab1
Morpholinos cdc42 MO1 cdc42 MO1 cdc42 MO1
ORFs cdc42 ORF2 cdc42.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556