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Summary Expression Gene Literature (6) GO Terms (54) Nucleotides (664) Proteins (43) Interactants (233) Wiki
XB-GENEPAGE-969572
Gene Symbol:
vcp

Gene Name:
valosin containing protein

Synonyms:
p97 ATPase ( Add synonyms , Nomenclature history )

Gene Function:
AAA+-type ATPase

Protein Function :
Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
inclusion body myopathy with Paget disease of bone and frontotemporal dementia [+]

OMIM:
INCLUSION BODY MYOPATHY WITH EARLY-ONSET PAGET DISEASE WITH OR WITHOUT FRONTOTEM [+]

External Links:
 
Xenbase Gene ID XB-GENE-969573 XB-GENE-17335247 XB-GENE-969578
Gene Symbol vcp vcp.L vcp.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448177
108718919
380491
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine vcp vcp.L vcp.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards VCP OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Vcp MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Vcp Ensembl
zebrafish
ZFIN, AGR vcp ZFIN Ensembl
chicken
GEISHA VCP Ensembl
fruit fly
Publications
First Phosphorylation of p97(VCP) and p47 in vitro by p34cdc2 kinase., Eur J Cell Biol 1999  
Most Recent Polyubiquitylation drives replisome disassembly at the termination of DNA replication., Science 2014  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 53 terms 0 term 33 terms
PANTHER vcp
KEGG Pathways K13525 K13525
KOG [O] AAA+-type ATPase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks vcp
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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