Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (119) GO Terms (8) Nucleotides (114) Proteins (20) Interactants (272) Wiki
XB-GENEPAGE- 970101

Gene Symbol: ptpa

Gene Name: protein phosphatase 2 phosphatase activator

Synonyms: pp2a , pr53 , Protein phosphatase 2a , ppp2r4
Add Xenopus synonyms , Nomenclature history

Gene Function: Phosphotyrosyl phosphatase activator

Protein Function :
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
  
 

Xenbase Gene ID XB-GENE-970102 XB-GENE-970106 XB-GENE-17346000
Gene Symbol ptpa ptpa.L ptpa.S
Chromosome Chr08 Scaffold46
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.14675 Xl.8828
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine ptpa ptpa.L ptpa.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PTPA OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ptpa MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ptpa ZFIN Ensembl
chicken
GEISHA PTPA Ensembl
fruit fly
FLYBASE Ptpa Ensembl
worm
WORMBASE
Publications
First: Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. [Nature 1988]
Most recent: Flexibility vs. robustness in cell cycle regulation of timing of M-phase entry in Xenopus laevis embryo cell-free extract. [Int J Dev Biol 2016]
View All Papers 5 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 3 terms 0 term
PANTHER ptpa
KEGG Pathways K17605
KOG [DT] Phosphotyrosyl phosphatase activator
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF ptpa.L ORF1
Affymetrix 1.0 Str.14675.1.S1_at Xl.13693.1.A1_at [+]
Affymetrix 2.0 Xl2.8828.1.S1_at

Symbol legend[+]
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.9.2
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556