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Summary Expression Gene Literature (130) GO Terms (28) Nucleotides (122) Proteins (28) Interactants (311) Wiki
XB-GENEPAGE-970101
Gene Symbol:
ptpa

Gene Name:
protein phosphatase 2 phosphatase activator

Synonyms:
pp2a , pr53 , Protein phosphatase 2a , ppp2r4 ( Add synonyms , Nomenclature history )

Gene Function:
Phosphotyrosyl phosphatase activator

Protein Function :
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.


InterPro :
PTPA sf , Phstyr phstse ac , WD40 repeat , WD40 repeat dom [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-970102 XB-GENE-970106 XB-GENE-17346000
Gene Symbol ptpa ptpa.L ptpa.S
Chromosome Chr8 Scaffold46
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100125159
734552
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ptpa ptpa.L ptpa.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PTPA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ptpa MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ptpa Ensembl
zebrafish
ZFIN, AGR ptpa ZFIN Ensembl
chicken
GEISHA PTPA Ensembl
fruit fly
FLYBASE Ptpa Ensembl
worm
Publications
First Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II., Nature 1988  
Most Recent Bistable, Biphasic Regulation of PP2A-B55 Accounts for the Dynamics of Mitotic Substrate Phosphorylation., Curr Biol 2021                                
All View All Papers 5 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 3 terms 0 term
PANTHER ptpa
KEGG Pathways K17605
KOG [DT] Phosphotyrosyl phosphatase activator
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ptpa
ORFs ptpa.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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