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Summary Expression Gene Literature (18) GO Terms (7) Nucleotides (1014) Proteins (41) Interactants (811) Wiki
XB-GENEPAGE-970615
Gene Symbol:
ywhaz

Gene Name:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

Synonyms:
14-3-3 zeta , 14-3-3zeta , 14-3-3z , ywhaz-a , ywhaz-b ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction

Protein Function :
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or ph...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-970616 XB-GENE-6256657 XB-GENE-970622
Gene Symbol ywhaz ywhaz.L ywhaz.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 394780
379608
379809
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot Swiss-Prot RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ywhaz ywhaz.L ywhaz.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen ttpa004p03      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards YWHAZ OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ywhaz MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ywhaz Ensembl
zebrafish
ZFIN, AGR ywhaz ZFIN Ensembl
chicken
GEISHA YWHAZ Ensembl
fruit fly
worm
Publications
First Activation of Raf-1 by 14-3-3 proteins., Nature 1994  
Most Recent A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway., Front Physiol 2019                    
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 3 terms 1 terms
PANTHER ywhaz
KEGG Pathways K16197 K16197 K16197
KOG [O] Multifunctional chaperone (14-3-3 family)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ywhaz
Antibodies ywhaz Ab1 ywhaz Ab1
Morpholinos ywhaz MO1 , ywhaz MO2 ywhaz MO1 , ywhaz MO2 ywhaz MO1 , ywhaz MO2
ORFs ywhaz ORF1 ywhaz.L ORF1 ywhaz.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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