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Summary Expression Gene Literature (2) GO Terms (9) Nucleotides (101) Proteins (24) Interactants (15) Wiki
XB-GENEPAGE- 971728

Gene Symbol: unc45b

Gene Name: unc-45 myosin chaperone B

Synonyms: cmya4 , unc45 , smunc45 , dicky ticker
Add Xenopus synonyms , Nomenclature history


Gene Function: Myosin assembly protein/sexual cycle protein and related proteins

Protein Function:
Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell assembly. Is necessary for normal early lens devel...[+]


Interactants: Loading ...

OMIM Disease Associations:
1/2
 
Xenbase Gene ID XB-GENE-971729 XB-GENE-17343539 XB-GENE-971733
Gene Symbol unc45b unc45b.L unc45b.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.11279 Xl.1302
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 4 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine unc45b unc45b.L unc45b.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards UNC45B OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Unc45b MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN unc45b ZFIN Ensembl
chicken
GEISHA UNC45B Ensembl
fruit fly
worm
WORMBASE
Publications
First: Paralysis and delayed Z-disc formation in the Xenopus tropicalis unc45b mutant dicky ticker. [BMC Dev Biol 2010]
Most recent: Contractile activity is required for Z-disc sarcomere maturation in vivo. [Genesis 2015]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 0 term 4 terms
EC
PANTHER unc45b
KEGG Pathways K21991 K21991 K21991
KOG [ODR] Myosin assembly protein/sexual cycle protein and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino unc45b MO1 , unc45b MO2 unc45b MO1 , unc45b MO2 unc45b MO1 , unc45b MO2
ORF unc45b ORF1
Affymetrix 1.0 Str.11279.1.S1_at Xl.9950.1.A1_at [+]
Affymetrix 2.0 Xl2.1302.1.S1_at

Symbol legend[+]

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