Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (190) GO Terms (14) Nucleotides (326) Proteins (45) Interactants (1220) Wiki
XB-GENEPAGE-972521
Gene Symbol:
pcna

Gene Name:
proliferating cell nuclear antigen

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
DNA polymerase delta processivity factor (proliferating cell nuclear antigen)

Protein Function :
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading ...[+]



Interactants:
Loading ...

Diseases: 


OMIM:
ATAXIA-TELANGIECTASIA-LIKE DISORDER 2; ATLD2

External Links:
1/3
 
Xenbase Gene ID XB-GENE-972522 XB-GENE-17342178 XB-GENE-972527
Gene Symbol pcna pcna.L pcna.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 493302
398425
394328
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine pcna pcna.L pcna.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PCNA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pcna MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pcna Ensembl
zebrafish
ZFIN, AGR pcna ZFIN Ensembl
chicken
GEISHA PCNA Ensembl
fruit fly
FLYBASE PCNA Ensembl
worm
Publications
First DNA replication and cell cycle control in Xenopus egg extracts., J Cell Sci Suppl 1989  
Most Recent Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma., Mol Ther Nucleic Acids 2020              
All View All Papers 13 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 5 terms 9 terms
PANTHER pcna
KEGG Pathways K04802 K04802 K04802
KOG [L] DNA polymerase delta processivity factor (proliferating cell nuclear antigen)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pcna
Antibodies Pcna Ab1 , Pcna Ab2 , Pcna Ab3 , Pcna Ab4 , Pcna Ab5 Pcna Ab1 Pcna Ab1 , Pcna Ab2 , Pcna Ab3 , Pcna Ab4 , Pcna Ab5
Morpholinos pcna MO1 pcna MO1 pcna MO1
ORFs pcna ORF1 MGC53867 ORF1 pcna.S ORF1
Clones Horizon Source BioScience Horizon EXRC Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556