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Summary Expression Gene Literature (197) GO Terms (19) Nucleotides (328) Proteins (47) Interactants (1249) Wiki
XB-GENEPAGE-972521
Gene Symbol:
pcna

Gene Name:
proliferating cell nuclear antigen

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
DNA polymerase delta processivity factor (proliferating cell nuclear antigen)

Protein Function :
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading ...[+]


InterPro :
CAP-Gly domain , CAP-Gly dom sf , CLIP1 ZNF , SP-C [+]

Interactants:
Loading ...

Diseases: 


OMIM:
ATAXIA-TELANGIECTASIA-LIKE DISORDER 2; ATLD2

External Links:
1/3
 
Xenbase Gene ID XB-GENE-972522 XB-GENE-17342178 XB-GENE-972527
Gene Symbol pcna pcna.L pcna.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493302
398425
394328
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pcna pcna.L pcna.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards PCNA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pcna MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pcna Ensembl
zebrafish
ZFIN, AGR pcna ZFIN Ensembl
chicken
GEISHA PCNA Ensembl
fruit fly
FLYBASE PCNA Ensembl
Publications
First DNA replication and cell cycle control in Xenopus egg extracts., J Cell Sci Suppl 1989  
Most Recent Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience., Neuron 2021  
All View All Papers 13 paper(s) referencing morpholinos 8 paper(s) referencing OMIMs 16 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 5 terms 9 terms
PANTHER pcna
KEGG Pathways K04802 K04802 K04802
KOG [L] DNA polymerase delta processivity factor (proliferating cell nuclear antigen)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pcna
Antibodies Pcna Ab1 , Pcna Ab2 , Pcna Ab3 , Pcna Ab4 , Pcna Ab5 Pcna Ab1 Pcna Ab1 , Pcna Ab2 , Pcna Ab3 , Pcna Ab4 , Pcna Ab5
Morpholinos pcna MO1
ORFs pcna ORF1 MGC53867 ORF1 pcna.S ORF1
Clones Horizon Source BioScience Horizon EXRC Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info