Gene Symbol: gtf2a1l [provisional] Gene Name: general transcription factor IIA, 1-like [provisional] Synonyms: alf Add Xenopus synonyms Gene Function: RNA polymerase II transcription initiation factor TFIIA, large chain Interactants: gtf2a1(2) , col2a1(1) , cyp26a1(1) , krt5.5(1) , mag(1) , magainins(1) , sftpc(1) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001045748|Xenopus (Silurana) tropicalis general transcription factor IIA, 1-like (gtf2a1l), mRNA CGGAGAGTTAGCATGGCCCATTCTGCCAACCCCAATCCTGTGCCAAAGCTATACAAATCAATTATTGAAGATGTTATGGAAAGTGTCAGGGAACTTTTTGTGGAAGAAGGTGTGGATGAGCAAGTGCTTAAGGATTTAAAGCAATTATGGGAGATCAAGGTACTGCAGTCTAAAGCTACAGAAGGTTTCTTCAGAGACAACAGTGCCCCACAATTTGTCCTACAACTGCCACAGAATTTACATCACTCCCTTCACAGCTCAACAGGGAATAGGAATGTTACACATTTTTCAACTGGCGAAATGGGTACCTCTGGATCGAACAGTGCGTTTTCTCTTCCAGCGGGTATTACTTATCCAATTCATCTGCCAGCTGGAATGACTGTGCAGACTGCATCTGGTCAACTTTACAAAGTAACAGTGCCGGTGATGGTCACTCAAGCTCCAGGAGGGCCGCGAATACTTCAGCCACCTGTTCAACAGTTCTTCCAACATATTCGCCATCCTTCAGGGCATGCTGCAAGCAGCCAATACAGCAGAAATGCTTACATAGAACAAAAATGGCAGCAGCAACCGGCTCAGGTTCACAGTTCTGAAGGACTAAATATATATGATCAAGAGGCCACCATTGAACCTAATTATCAGAATAATAATAACGATGATTTGATTATTCAGCAGTCCATAGATTTGCAGCAGAATCTTACAAATAAGGGGCTTCATCAGCCCACAAACAGTTTGGAAGGCAGCAATTTAAATGAAATAACAGGGACGCTCTTTAGTCCTAGGCAGTCCAATGGAGGAATAGATCTGAACTCTGAGTCTGTGATGAATAACTTAAACATGGCTCATTCCTTGCAAGGACAACCGGAAAATGAATATGCAAGCCTGTTAAAATCTCAAGATTCCGATGATGTCGTTGAGCTAATACTAATGGATAATGAACTTGGTGATAAAACTTCCACAGGAGACAGTGGGAACGTTGGCATCCAGACTGGGATATCTAATGTGGAGAAGCAAGCAGTACCCCGTGAAATAGAGATCATTCAAGTTGATGGGACCGGTGACACTTCCTCTGATGAAGACCTTGGAAATGTGAGAGACCTAGATGAAAATGATTTTTTGGGCATTATTGACACAGAGGATCTTAAAGCTCTAGAAGAAGATGATACTGCATCAAATGACTCAACTAGTAATAGTAGTGATGATGAGGATCCGGAAATTGATGTCATTGAAGAGGATCCATTAAATTCTGGAGATGATGTGAGTGAGCAAGAAGTCCCAGACTTGTTTGATACTGACAATGTCATTGTGTGTCAGTATGATAAGATTCATCGAAGTAAAAACAAGTGGAAATTCTATTTAAAAGATGGAGTCATGAGTTTTGGTGGGAAAGATTATGTTTTTTCTAAAGCCATTGGGGAAGCTGAATGGTGATAACCAGAACGCTTTTCCACGGTGTTTAACTTGCAAAGAAGAGAAGGAAGAAAAAAATTCATTTGTATTTTTCACCCAAGCATTCTGCACTTAATAATAATAATAACAGCAGAAACAATATCAATTTTGTTGTTTTCTTTAAGTTAAATTTGCATCCTTATGAGTGAAATCTACATATTTTTTGTGTTGCAGCAGATATGAAATAAATATAATTATGCAGTAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001089286|Xenopus laevis general transcription factor IIA, 1-like (gtf2a1l), mRNA CGTCAGCGAACGCCCAACGCGTTACGTCAGACCGCAGGCGATTGAACGTGGTTCCATCTTCCGGTTAGGCCTGACTGTGATCATGGCCCATTCGGCTAACCCTAATCCTGTGCCAAAGTTATACAAATCAATTATTGAAGATGTCATGGAAAGTGTTCGGGAAATTTTTGTGGAAGAAGGCGTGGATGAGCAAGTGCTTAAGGAATTAAAGCAGTTATGGGAGACCAAGCTACTGCAGTCGAAAGCTACAGAAGGTTTCTTCCAAGACAACAGCACCCCACAATTTGTCCTCCAACTGCCTCAGAATTTGCATCACTCCCTTCACACCTCAACAGGAAATCGAAATGTTACACATTTTGCAACAGGTGAAATGGGTACTTCCGGATCAAACAGTGCATTTTCTCTTCCGGCGGGTATTACTTACCCGATTCATCTGCCAGCTGGAATGACTGTACAAACTGCCTCTGGTCAACTTTACAAAGTAACAGTGCCTGTAATGGTCACCCAAGCTCCCGGGGGCCCGAGAATACTCCAGCCGCCAGTTCAGCAGTTCTTTCAACATGTCCGTCAACCTTTAGGGCCCTCCTCAAGCAGCCAGTACAGCAGAAATACTTACATAGAACAAAAATGGCAGCAGCAACCGGCCAACGTTCACAGCTCCGAAGGACTAAATATATATGATCGAGAGGCCTCTGTTGAACCGAATTATCAGAATAATAATGATGATTTGCTTATTCAGCAGTCCGTAGATCTGCAGGATCATCTTACAAACAAGGTTCTGAATCAGCCCACGCACGGCTTGGAAGACAGTCATTTAAATGATATAACAGGACCGCTCTTTAGTCCAAGGCAAATGAATGGAGGACTAGATCTGAGCTCGGAGTCTGTGATGAATAACTTAAACATGGCTCACTCCATGCAAGGGCAACCGGAGCATGAATATTCAAGCCTGTTAAAACCACAAGATTCTGACGATGTAGTTGAGCTGATACTTATGGATAATGAACTTGGTGATAAAAATTCTGCTGGAGACAACGGGAACATTGACATCCCTAATGGGTTACCTGGTGTGGAGAAGCAAGCAGTACCCCGGGAAATAGAGATAATTCAAGTAGATGGGGCCGGCGACACTTCCTCTGATGAAGACCTAGGAAATGTGAGAGACCTAGATGAAAATGAATTTTTGGGCATTATTGACACAGAGGACCTTAAAGCTCTAGAAGAGGATGACACTGGGTCAAATGAAGACTCGACTAGTAACAGTAGTGATGATGAGGATCCAGAAATCGATGTGATTGAAGAGGATCCATTAAATTCTGGAGATGACGTGAGTGAGCAAGAAGTCCCGGATTTGTTTGACACCGACAATGTCATTGTGTGCCAGTATGATAAGATTCATCGAAGCAAAAACAAGTGGAAATTCTATTTAAAAGATGGAGTTATGAGTTTCGGTGGCAAAGACTACGTTTTTTCTAAAGCCATTGGAGAAGCGGAATGGTGATCACTGGAGTGTTTTCCGCGGAGCTTAACTTGCAGAGAAGAGTATTTTTCATAGAAACATTCTGCACTTAAAAAAAAAAAAACACAAATAAGTTAACTTTTTGTCATTTTCTTTGAGTTAATTTAAGTTTTATGTTTATGAATGATATAATTCTATGTATTTTTCTGTTGCAACAGATGTGAAATAAAGTTAATAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001039213|general transcription factor IIA, 1-like [Xenopus (Silurana) tropicalis] MAHSANPNPVPKLYKSIIEDVMESVRELFVEEGVDEQVLKDLKQLWEIKVLQSKATEGFFRDNSAPQFVLQLPQNLHHSLHSSTGNRNVTHFSTGEMGTSGSNSAFSLPAGITYPIHLPAGMTVQTASGQLYKVTVPVMVTQAPGGPRILQPPVQQFFQHIRHPSGHAASSQYSRNAYIEQKWQQQPAQVHSSEGLNIYDQEATIEPNYQNNNNDDLIIQQSIDLQQNLTNKGLHQPTNSLEGSNLNEITGTLFSPRQSNGGIDLNSESVMNNLNMAHSLQGQPENEYASLLKSQDSDDVVELILMDNELGDKTSTGDSGNVGIQTGISNVEKQAVPREIEIIQVDGTGDTSSDEDLGNVRDLDENDFLGIIDTEDLKALEEDDTASNDSTSNSSDDEDPEIDVIEEDPLNSGDDVSEQEVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMSFGGKDYVFSKAIGEAEW	Refseq >NP_001082755|TFIIA-alpha and beta-like factor [Xenopus laevis] MAHSANPNPVPKLYKSIIEDVMESVREIFVEEGVDEQVLKELKQLWETKLLQSKATEGFFQDNSTPQFVLQLPQNLHHSLHTSTGNRNVTHFATGEMGTSGSNSAFSLPAGITYPIHLPAGMTVQTASGQLYKVTVPVMVTQAPGGPRILQPPVQQFFQHVRQPLGPSSSSQYSRNTYIEQKWQQQPANVHSSEGLNIYDREASVEPNYQNNNDDLLIQQSVDLQDHLTNKVLNQPTHGLEDSHLNDITGPLFSPRQMNGGLDLSSESVMNNLNMAHSMQGQPEHEYSSLLKPQDSDDVVELILMDNELGDKNSAGDNGNIDIPNGLPGVEKQAVPREIEIIQVDGAGDTSSDEDLGNVRDLDENEFLGIIDTEDLKALEEDDTGSNEDSTSNSSDDEDPEIDVIEEDPLNSGDDVSEQEVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMSFGGKDYVFSKAIGEAEW

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		[+] Str.19885	Xl.29766
Unigene EST Profile			EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	GTF2A1L
mouse		MGI	Gtf2a1l
zebrafish

Publications
First:		Mutagenesis in the switch IV of the helical domain of the human Gsalpha reduces its GDP/GTP exchange rate. [J Cell Biochem 2000]
Most recent:		Sevoflurane inhibits the µ-opioid receptor function expressed in Xenopus oocytes. [Pharmacology 2011]
		View All Papers

Functional Ontologies
GO: Molecular:		transcription initiation factor activity
Biological:		transcription initiation from RNA polymerase II promoter
Cellular Component:		nucleus
EC:
KOG:		[K] RNA polymerase II transcription initiation factor TFIIA, large chain

Reagents		tropicalis	laevis
Clones			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0		Str.19885.1.S1_at
Affymetrix 2.0			Xl2.29766.1.S1_at

Symbol legend[+]

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