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Summary Expression Gene Literature (66) GO Terms (30) Nucleotides (235) Proteins (29) Interactants (677) Wiki
XB-GENEPAGE-973459

Gene Symbol: vangl2

Gene Name: VANGL planar cell polarity protein 2

Synonyms: stb1 , Strabismus , lpp1 , ltap , stbm , stbm1 , Van Gogh , vang-like 2 , vangl2-a , vangl2-b ( Add synonyms , Nomenclature history )

Gene Function: Non-canonical wnt pathway signaling protein

Protein Function :
Has a role in non-canonical Wnt/planar cell polarity (PCP) signaling; can recruite dvl/dsh and prickle from the cytoplasm to the plasma membrane. Acts in a PCP complex to regulate the polarized assembl...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases: NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO; NTD

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Xenbase Gene ID XB-GENE-973460 XB-GENE-6251797 XB-GENE-973465
Gene Symbol vangl2 vangl2.L vangl2.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL Swiss-Prot RefSeq TrEMBL Swiss-Prot RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine vangl2 vangl2.L vangl2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards VANGL2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Vangl2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR vangl2 ZFIN Ensembl
chicken
GEISHA VANGL2 Ensembl
fruit fly
worm
WORMBASE
Publications
First Eye-specific segregation of optic afferents in mammals, fish, and frogs: the role of activity., Cell Mol Neurobiol 1985  
Most Recent Vangl2 coordinates cell rearrangements during gut elongation., Dev Dyn 2019                  
All View All Papers 8 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 29 terms 3 terms 3 terms
PANTHER vangl2
KEGG Pathways K04510 K04510 K04510
KOG [T] Signaling protein van gogh/strabismus
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Vangl2 Ab1 , Vangl2 Ab2 , Vangl2 Ab3 , Vangl2 Ab4 , Vangl2 Ab5 Vangl2 Ab1 , Vangl2 Ab2 , Vangl2 Ab3 , Vangl2 Ab4 , Vangl2 Ab5 Vangl2 Ab1 , Vangl2 Ab2 , Vangl2 Ab3 , Vangl2 Ab4 , Vangl2 Ab5
Morpholino vangl2 MO1 , vangl2 MO2 , vangl2 MO3 , vangl2 MO4 , vangl2 MO5 , vangl2 MO6 , Vangl2-MO7 vangl2 MO1 , vangl2 MO2 , vangl2 MO3 , vangl2 MO4 , vangl2 MO5 , vangl2 MO6 , Vangl2-MO7 vangl2 MO1 , vangl2 MO2 , vangl2 MO3 , vangl2 MO4 , vangl2 MO5 , vangl2 MO6 , Vangl2-MO7
ORF vangl2.L ORF1 vangl2.S ORF1
Affymetrix 1.0 Str.11014.1.S2_at [+] Xl.10610.1.S1_at Xl.5981.1.S1_at
Affymetrix 2.0 Xl2.10610.1.S2_at [+] Xl2.5981.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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