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Summary Expression Gene Literature (56) GO Terms (11) Nucleotides (229) Proteins (28) Interactants (283) Wiki
XB-GENEPAGE- 973459

Gene Symbol: vangl2

Gene Name: VANGL planar cell polarity protein 2

Synonyms: stb1 , Strabismus , lpp1 , ltap , stbm , stbm1 , Van Gogh , vang-like 2 , vangl2-a , vangl2-b
Add Xenopus synonyms , Nomenclature history


Gene Function: Non-canonical wnt pathway signaling protein

Protein Function:
Has a role in non-canonical Wnt/planar cell polarity (PCP) signaling; can recruit dvl/dsh and prickle from the cytoplasm to the plasma membrane. Acts in a PCP complex to regulate the polarized assembly...[+]


Interactants: YYY

OMIM Disease Associations: NEURAL TUBE DEFECTS
1/2
 
Xenbase Gene ID XB-GENE-973460 XB-GENE-6251797 XB-GENE-973465
Gene Symbol vangl2 vangl2.L vangl2.S
Chromosome scaffold_8c chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.11014 Xl.10610 Xl.5981
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 30 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine vangl2 vangl2.L vangl2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards VANGL2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Vangl2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN vangl2 ZFIN Ensembl
chicken
GEISHA VANGL2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Eye-specific segregation of optic afferents in mammals, fish, and frogs: the role of activity. [Cell Mol Neurobiol 1985]
Most recent: hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus. [Dev Biol 2017]
View All Papers 8 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 9 terms 8 terms
EC
PANTHER vangl2
KEGG Pathways K04510 K04510 K04510
KOG [T] Signaling protein van gogh/strabismus
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Vangl2 Ab1 , Vangl2 Ab2 , Vangl2 Ab3 Vangl2 Ab1 , Vangl2 Ab2 , Vangl2 Ab3 Vangl2 Ab1 , Vangl2 Ab2 , Vangl2 Ab3
Morpholino vangl2 MO1 , vangl2 MO2 , vangl2 MO3 , vangl2 MO4 , vangl2 MO5 , vangl2 MO6 vangl2 MO1 , vangl2 MO2 , vangl2 MO3 , vangl2 MO4 , vangl2 MO5 , vangl2 MO6 vangl2 MO1 , vangl2 MO2 , vangl2 MO3 , vangl2 MO4 , vangl2 MO5 , vangl2 MO6
ORF vangl2 ORF1 vangl2 ORF2
Affymetrix 1.0 Str.11014.1.S2_at [+] Xl.10610.1.S1_at Xl.5981.1.S1_at
Affymetrix 2.0 Xl2.10610.1.S2_at [+] Xl2.5981.1.S1_at

Symbol legend[+]

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