[provisional- machine annotated only] Gene Symbol: cdc6 [Predicted: Source is Human Entrez Gene] Gene Name: cell division cycle 6 [Predicted: Source is Human Entrez Gene] Synonyms: xcdc6 Add Xenopus synonyms Gene Function: Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase Interactants: mcm2(27) , cdt1(23) , gmnn(16) , cdk2(15) , cdc7(11) , cdc45(7) , orc2(7) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001007993|Xenopus (Silurana) tropicalis cell division cycle 6 homolog (cdc6), mRNA CTCGGAGAGGAAGCGGTGAGAGCTGCGAGTTGTTACTTCCAACTGAATTCAGTCACACTATCGCTGAGAAGCCGCAATGCCAAGCACCAGGTCTCAGTCTCAAAGCGCCATTCAGTTTCCCAAGAAAAAAAATGCTCGAACGCACACCAAAGAGGCCTCCCGTGAAAGGACCAAATTGGAAAACGGCTCCTCTGTCGCGCTGCCACTCTCTCCACTTCCCAAAGAGCTTCCCCTGAGTCCAAGGAAACGACTTGGTGATGACAATCTTTGCAATGTTCCCCAGACATTAAGCTGCTCACCACCCAAGCAGTCTCGCAAAGAGAATGGCCCGCCAAGCACCCCTAAGGGACGCCGGTTACTTTTTGACGAGAACCAGTCGGCAACAACACCTGTATCTCCTCTCAAGAGGGTGCAGGATCCTTATTTGCTGTCCCCTTTGAGAAGGGGGCAAGAGACACCATCCAGCTCTCGCAACAACGAGAGGAAGAGTGTGGGTGCCCGGCTATTTAAACAGGAGGGTTCTTGCTATCAGAAGGCTAAGCATGCTTTGAATACAGCTATACCAGAGCGTCTATTGGCCCGTGACAGTGAGACTGCGACTATCAAGGCCTTCCTGACAAGTCATGTCTCTGGTGGGAAGCCAGGAAGCCTTTACATATCTGGTGCTCCAGGAACTGGCAAAACGGCTTGCTTGAATAAGCTGCTGCAGGAGAGCAAGGATGACCTCAAGCAATGCAAGACGGTTTACATCAACTGCATGTCATTGCGCAGCTCCCAGGCGGTGTTTCCGGCCATAGCTGAAGAAATCTCTGGTGGAAAATCTTCAATTGCTGCAAAAGATATTGTTAGGAGTTTGGAGAAGACGGTGACTTCAAAGGGCCCAATCATCCTGCTGGTGCTGGATGAGATGGATCAGCTCGATAGTCGAGGACAGGATGTCTTATACACAGTGTTTGAGTGGCCCTGGCTTCCAAATTCTAGGGTGGTTCTTATTGGCATTGCTAACGCGTTAGATTTGACAGACCGTATTCTGCCTAGGCTACAAGCTCGACCTCAGTGCAAGCCACAGCTGCTTAACTTCTCTCCGTATACAAAGGATCAGATTGCTACCATTCTGCAGGAGAGACTAAATCAGGTTTCAGGTGACCAGGTTCTGGATAATGCTGCTATTCAGTTTTGTGCCAGGAAAATTTCAGCAGTCTCTGGAGATGCTCGAAAGGCACTAGACATCTGCAGGAGAGCTGTTGAAATTGTTGAAGCGGATGTAAGGGGCCAGACTGTCCTCAAGCCGCTAACTGAAAGTCTCTCTCCTAGTAAGGAAGTTCCATCAAACCCTGTTCCAAAAAAAGTCAGCCTTCCACACATCTCCCGTGTCCTGTCAGATGTATATGGGGACAAGATGGCAAGCAGTGGGGGGTCAAGCGAGAGCTTTCCCTTACAACAGAAACTGCTGGTCTGTGCCCTGCTGCTGCTAACTCGACAGAGCAAGATCAAGGAAGTCACACTTGGCAAGTTGCACGAGGCATACAGTAAAGTCTGCCGAAAGCAGCAGGTTCCCGGCGTTGGGCAATCGGAGTGCCTGTCACTTTGTCAGCTCCTGGAGACAAGGGGCATTCTGGGGCTAAAGAAAGCCAAGGAGGCCCGGCTTACAAAGGTATCCCTCAAGATAGAGGAGCGGGATATTGAACATGCATTCAAAGATAAAGTTCTGATTGGAAATGTTCTGAATTCGGGGATATAATGTTTTGTTCTGCGTGTATCTCTGATGTAACTTCTGTAAATTTATGTACAATTTTAGCTAATGTATCTTTAGAATTTTATCAGTTTTATTTTTTGGACACGTGACTGTTTACACTTGTGTGGGTACTTTTTTTATTTATAAAGTGAAAAAAATTGCAGGCCCCTTTTTAAAGAACAGGCACTTGGTTTTATCCTATGCCTGGTTGTCTTCCATTTTTCAGCACAGTCATAAGTATGGAGGCTTTAAGTGTCTACACATGAAATAAACTCTAGTGTCTGTTGTAAATAGTTGGCGCTGAGGGCGCTGTTTATAATTTGCTGTCATAGACAGCAATGTTAATGTTTAAGTATCTGTAAGGTACGGTCCTGTTTGTGGTGGTCTCTCGTGGACATGGTGTCTTTATGACCTGGATTATACTTGCGTTTTAATCAAGACTCCTATTTTAATAAACGTTTAAAACATTAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001090971|Xenopus laevis cell division cycle 6 homolog (cdc6), mRNA AGAAGTAGCAGCGAGGGAAGAGCCTGGTTATTTCTGACTGAATTCGGACACAGCCTCGCTGACAAGTCGCCATGCCAAGCACCAGGTCTCAGTCTCAAAGTGCCATTCCGTTTCCCAAGAAGAAGAATGCTCAAAGTCGCAGCACAGAGGCCTCCCGTGCAAGAACCAAGTCAGAAAACTGCTCCACTCTCGCTCTGCCGCTCTCTCCGCTTCCCCTCAGTCCACGCAAACGATTGGGTGATGAAAACCTTTGCAACATTCCTCAGACATTAAGCTGCTCACCACCCAAGCAGTCTCGCAAAGAGAACGGCCAGACCTCCACCCCTAAGGGGCGCCGCTTGCTTTTTGATGAGAACCAGGCAGCAGCAGCAACACCAGTATCCCCCCTCAAGAAGGTACAGGATCCTTATAGACTGTCTCCTTTGAAAAGGGGGCAAGAGACACCATCCGGCTCTCGTAACCACAGGCTGCAGGAAAGGAAGACTGCTGGTGTCCAGCTATTTAAACAGGAAGGTTCTTGCTATCAGAAGGCTAAGCACGCTTTGAATACGGCCATACCAGAGCGCCTATTGGCTCGTGAGAGTGAGACTGCATTTATCAAGACCTTCTTGACAAGTCATGTTTCTGATGGGAAACCAGGAAGCCTTTACATATCTGGTGCTCCCGGAACTGGCAAAACGGCTTGCTTGAATAAGCTTCTGCAGGAGAGCAAGGATGACCTCCAGCAGTGCAAGACAGTTTACATCAACTGCATGTCATTGCGCAGCTCCCAGGCAGTGTTTCCGGCTATAGCTGAAGAAATCTCTGGGGGCAAATCTTCACTGGCCGCGAAAGATATTGTAAGGAGTTTGGAGAAGCTGGTGACTTCAAAGGGTCCAATCATCTTGCTGGTGTTGGATGAGATGGATCAGCTGGACAGCAGAGGACAGGATGTCTTGTACACCGTGTTTGAGTGGCCTTGGCTTACAAATTCTAGGATGGTTTTAATCGGCATTGCTAACGCATTGGATTTGACAGACCGTATTTTGCCCAGGCTACAAGCTCGACCTCGGTGCAGACCACAGTTGCTCAACTTTTCTCCATATACAAAGGATCAGATTGCTACCATTCTACAGGACAGACTGAATACGGTTTCAGGCGATCAAGTTCTGGATAATGCTGCTATTCAGTTCTGTGCAAGGAAAATCTCTGCTGTCTCTGGAGATGCTCGAAAGGCGCTAGATATCTGCAGGAGAGCTGTTGAAATTGTCGAAGCGGATGTCAGGGGCCAGACTGTCCTTAAGCCTCTAACTGAATGTGCGTCTCCTTGTAAAGAAGTCCCATTAAACCCTGTTCCAAAAAAGGTCAGCCTTCCACACATCTCTCGTGTCCTGTCAGATGTGTATGGGGACAAGATGGCAAGCCGTGAGGGTTCAAGCGAGAGTTTTCCCTTACAGCAGAAACTGCTGGTCTGTGCCCTGCTCCTAATAACTCGGCAAAGCAAGATCAAGGAAGTCACACTTGGCAAGGTGCATGAGGCATACAGTAAAGTCTGCCGAAAGCAACAGGTGCCTGGAGTCGGCCAATCAGAGTGCCTGTCGCTTTGTCAGCTCCTAGAGACAAGGGGTATTCTGGGGCTAAAGAAAGCCAAGGAGGCCCGGCTTACAAAGGTGTCCCTCAAGATAGAGGAGCGGGATGTTGAGCACGCATTCAAGGATAAAGTTCTAATAGGCAATGTTCTGAATTCAGGCATTTAATGGCCGTTTTATTCTACTTTTTATCCGTCACTTCTGTAAATTTTATGTACAATTTTATCCTCTAATGTATATTTAGAGCTTTTTTTGGACACATGACTGTTTTATACTTAACCACAAATACCTTTTCTGTGGGTACCTTTTTATATGGAGGGGAAAAAAATCACAGGTTTTAAAGGACAGGCAATCAGGTTTTTACAATGTCTTCCATTGCTTTGTACAGTCATAAGGATTGACGTGTTGATAAAGTATCTGCACATGAAATACCTCCTAGTGTCTGCTGTAAATAGTATGTTTTTAATTTGCTGTCCCGTGCAGCAGATGTTAATGTTGAAGTATCTGTAAGGTACGGCCCTGTTTCTCTCATCTTTTATGGACAAGGTGTCTTTATTCCCTGGATTTTACTTGCGTTTTATTCAAGACTCCACTTCTGTTTTAATAAAAATTAAAACATTAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001007994|cell division cycle 6 homolog [Xenopus (Silurana) tropicalis] MPSTRSQSQSAIQFPKKKNARTHTKEASRERTKLENGSSVALPLSPLPKELPLSPRKRLGDDNLCNVPQTLSCSPPKQSRKENGPPSTPKGRRLLFDENQSATTPVSPLKRVQDPYLLSPLRRGQETPSSSRNNERKSVGARLFKQEGSCYQKAKHALNTAIPERLLARDSETATIKAFLTSHVSGGKPGSLYISGAPGTGKTACLNKLLQESKDDLKQCKTVYINCMSLRSSQAVFPAIAEEISGGKSSIAAKDIVRSLEKTVTSKGPIILLVLDEMDQLDSRGQDVLYTVFEWPWLPNSRVVLIGIANALDLTDRILPRLQARPQCKPQLLNFSPYTKDQIATILQERLNQVSGDQVLDNAAIQFCARKISAVSGDARKALDICRRAVEIVEADVRGQTVLKPLTESLSPSKEVPSNPVPKKVSLPHISRVLSDVYGDKMASSGGSSESFPLQQKLLVCALLLLTRQSKIKEVTLGKLHEAYSKVCRKQQVPGVGQSECLSLCQLLETRGILGLKKAKEARLTKVSLKIEERDIEHAFKDKVLIGNVLNSGI	Refseq >NP_001084440|cell division cycle 6 homolog [Xenopus laevis] MPSTRSQSQSAIPFPKKKNAQSRSTEASRARTKSENCSTLALPLSPLPLSPRKRLGDENLCNIPQTLSCSPPKQSRKENGQTSTPKGRRLLFDENQAAAATPVSPLKKVQDPYRLSPLKRGQETPSGSRNHRLQERKTAGVQLFKQEGSCYQKAKHALNTAIPERLLARESETAFIKTFLTSHVSDGKPGSLYISGAPGTGKTACLNKLLQESKDDLQQCKTVYINCMSLRSSQAVFPAIAEEISGGKSSLAAKDIVRSLEKLVTSKGPIILLVLDEMDQLDSRGQDVLYTVFEWPWLTNSRMVLIGIANALDLTDRILPRLQARPRCRPQLLNFSPYTKDQIATILQDRLNTVSGDQVLDNAAIQFCARKISAVSGDARKALDICRRAVEIVEADVRGQTVLKPLTECASPCKEVPLNPVPKKVSLPHISRVLSDVYGDKMASREGSSESFPLQQKLLVCALLLITRQSKIKEVTLGKVHEAYSKVCRKQQVPGVGQSECLSLCQLLETRGILGLKKAKEARLTKVSLKIEERDVEHAFKDKVLIGNVLNSGI

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.55497 [+] Str.4902	Xl.61272
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		2 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CDC6
mouse		MGI	Cdc6	All(2) Targeted, other(2)
zebrafish

Publications
First:		Replication origins in eukaroytes. [Curr Opin Genet Dev 1996]
Most recent:		Cdc6 is required for meiotic spindle assembly in Xenopus oocytes. [Cell Cycle 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding nucleoside-triphosphatase activity nucleotide binding
Biological:
Cellular Component:
EC:
KOG:		[LD] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.8648.1.S1_at [+] Str.4902.1.A1_at	Xl.23442.1.A1_at
Affymetrix 2.0			Xl2.25641.1.S2_at

Symbol legend[+]

- Blast this sequence
   - Literature Or Expression Images