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Summary Expression Gene Literature (95) GO Terms (10) Nucleotides (552) Proteins (49) Interactants (311) Wiki
XB-GENEPAGE-974719
Gene Symbol:
cdc6

Gene Name:
cell division cycle 6

Synonyms:
xcdc6 ( Add synonyms , Nomenclature history )

Gene Function:
Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase

Protein Function :
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.


InterPro :
Cdc6/18 , P-loop NTPase , WH DNA-bd sf , WH-like DNA-bd sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Meier-Gorlin syndrome

OMIM:
MEIER-GORLIN SYNDROME 5; MGORS5

External Links:
 
Xenbase Gene ID XB-GENE-974720 XB-GENE-974724 XB-GENE-17346530
Gene Symbol cdc6 cdc6.L cdc6.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493356
403388
398082
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cdc6 cdc6.L cdc6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards CDC6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cdc6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cdc6 Ensembl
zebrafish
ZFIN, AGR cdc6 ZFIN Ensembl
chicken
GEISHA CDC6 Ensembl
fruit fly
FLYBASE Cdc6 Ensembl
Publications
First Replication origins in eukaroytes., Curr Opin Genet Dev 1996  
Most Recent Mathematical Model Explaining the Role of CDC6 in the Diauxic Growth of CDK1 Activity during the M-Phase of the Cell Cycle., Cells 2019                  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 3 terms 3 terms
PANTHER cdc6
KEGG Pathways K02213 K02213 K02213
KOG [LD] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cdc6
Antibodies Cdc6 Ab2 , Cdc6 Ab1 , Cdc6 Ab3 Cdc6 Ab2 , Cdc6 Ab1 , Cdc6 Ab3
Morpholinos cdc6 MO1
ORFs cdc6 ORF1 cdc6.L ORF1 Xcdc6 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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