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XB-GENEPAGE-975698
Gene Symbol:
pcbd1
Gene Name: pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
Synonyms:
dcoh
,
Xdcoh
,
pcbd
,
pcd
,
phs
( Gene Function: Pterin carbinolamine dehydratase PCBD/dimerization cofactor of HNF1 Protein Function
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Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates th...[+]
Interactants:
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Diseases: Disease Ontology:
diabetes mellitus
OMIM:
HYPERPHENYLALANINEMIA, BH4-DEFICIENT, D; HPABH4D
External Links:
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Xenbase Gene ID | XB-GENE-975699 | XB-GENE-6252156 | XB-GENE-17331419 | |||||
Gene Symbol | pcbd1 | pcbd1.L | pcbd1.S | Chromosome | Chr7 | chr7L | Scaffold19 | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.2
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
496425
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496367
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397951
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | pcbd1 | pcbd1.L | pcbd1.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells., Proc Natl Acad Sci U S A 1984 |
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Most Recent |
[Analysis of PIH1D3 variant in a Chinese pedigree affected with primary ciliary dyskinesia]., Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 |
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All | View All Papers 3 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 3 terms | 2 terms | 4 terms | |||||
PANTHER | pcbd1 | |||||||
KEGG Pathways | K01724 | K01724 | ||||||
KOG |
[K] Pterin carbinolamine dehydratase PCBD/dimerization cofactor of HNF1
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | pcbd1 | |||||||
Morpholinos | pcbd1 MO1 | pcbd1 MO1 | pcbd1 MO1 | |||||
ORFs | pcbd1 ORF1 | LOC496367 ORF1 | pcbd1.L ORF1 | |||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
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