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Summary Expression Gene Literature (12) GO Terms (18) Nucleotides (104) Proteins (40) Interactants (212) Wiki
XB-GENEPAGE-976071
Gene Symbol:
hira

Gene Name:
histone cell cycle regulator

Synonyms:
tup1 , dgcr1 , tuple1 ( Add synonyms , Nomenclature history )

Gene Function:
Histone transcription regulator HIRA, Wrepeat superfamily

Protein Function :
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-976072 XB-GENE-17340716 XB-GENE-976075
Gene Symbol hira hira.L hira.S
Chromosome Chr1 Scaffold151 chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100495450
100049116
394341
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein Uniprot NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hira hira.L hira.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HIRA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hira MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hira Ensembl
zebrafish
ZFIN, AGR hira ZFIN Ensembl
chicken
GEISHA HIRA Ensembl
fruit fly
FLYBASE Hira Ensembl
worm
Publications
First Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms., Biochem J 1999  
Most Recent Histone variant H3.3 residue S31 is essential for Xenopus gastrulation regardless of the deposition pathway., Nat Commun 2020                  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 4 terms 6 terms
PANTHER hira
KEGG Pathways K11293 K11293
KOG [DK] Histone transcription regulator HIRA, Wrepeat superfamily
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hira
Morpholinos (on-target & off-target) hira MO1 hira MO1
Clones Horizon Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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