Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (14) GO Terms (36) Nucleotides (268) Proteins (36) Interactants (419) Wiki
XB-GENEPAGE-976426
Gene Symbol:
gpc4

Gene Name:
glypican 4

Synonyms:
K-glypican , Xgly4 , glypican-4 , knypek ( Add synonyms , Nomenclature history )

Gene Function:
heparin sulfate cell surface proteoglycan

Protein Function :
Cell surface proteoglycan that bears heparan sulfate.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Simpson-Golabi-Behmel syndrome type 1 [+]

OMIM:
WILMS TUMOR 1; WT1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-976427 XB-GENE-976431 XB-GENE-17337230
Gene Symbol gpc4 gpc4.L gpc4.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100126682
399356
108700175
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein RefSeq  More.. NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gpc4 gpc4.L gpc4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards GPC4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gpc4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gpc4 Ensembl
zebrafish
ZFIN, AGR gpc4 ZFIN Ensembl
chicken
GEISHA GPC4 Ensembl
fruit fly
Publications
First Identification of tissues and patterning events required for distinct steps in early migration of zebrafish primordial germ cells., Development 1999  
Most Recent Heparan Sulfate Proteoglycan Clustering in Wnt Signaling and Dispersal., Front Cell Dev Biol 2020      
All View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 36 terms 7 terms 7 terms
PANTHER gpc4
KEGG Pathways K08110 K08110 K08110
KOG [T] Heparin sulfate cell surface proteoglycan
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gpc4
Morpholinos gpc4 MO2 , gpc4 MO5 gpc4 MO1 , gpc4 MO2 , gpc4 MO5 gpc4 MO2
ORFs gpc4.L ORF1
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info