Gene Symbol: stx1a Gene Name: syntaxin 1A (brain) Synonyms: syntaxin 1A, sx1a, syntaxin1a Add Xenopus synonyms Gene Function: SNARE protein Syntaxin 1 and related proteins Interactants: snap25(15) , cacna1c(7) , cftr(7) , slc6a1(6) , cacna1b(5) , cav1(5) , kcnb1(5) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene
mRNA		Refseq >NM_001078723|Xenopus (Silurana) tropicalis syntaxin 1A (brain) (stx1a), mRNA AGCAGATTTGGGAGGAAGGCAGGAGACGGGAGCAGGGGCTGTGATTCCAGCAAGGAGACAGGGAAGTGGCACAGGAGGGAAGCACCACGGTACTCTCTCCATTTAGATACGTCAGGGCGGCAGTTAGGAGAAGCTGCATGTATGGCTGGCACTGAGTCTGTAAGAGGCAGCTGAACTACTGTGTGCAAACAGGTCCATCCGAGCTGTATATATGAGTGCAGTGTATTCGCACCCATCTTTATTCAGGGGACTGGGCTGCTGCTAGTAGGGAAGATATTAGGCACAGAGCTCCTTTCCCAGGCAAGTTGCAGGCAGGCACCTGTGTGTTCCAGACAGTCTGCCCCTATGTCAGACTGAGCCACAGCTTGCATCCGGCGAGTGTTCGGGAGAAGCCACACATCTGAGCAGATTATTGTGTGGCCCTGTGGGCTCCTGCTTGGGATCAGCATGAAGGATCGGACCAGGGAGCTACGTGCTGCAAAGGACAGCGATGAGGATGATGAGGTTACTGTGAGCTTGGATCGAGATCGTTTCATGGATGAATTTTTTGAACAGGTTGAAGAGATCAGAGGGTTCATTGACAAGATTGCTGAAAATGTGGAGGAAGTTAAAAGAAAACACAGCGCTATCCTCGCTTCACCCAACCCTGATGAGAAAACAAAGGCCGAGCTGGAAGAGCTGATGTCGGACATCAAAAAGACAGCCAACAAGGTCCGTTCCAAGCTGAAGGGTATTGAGCAGAGCATTGAACAGGAAGAAGCAATGAACCGCTCCTCAGCTGACTTGCGTATACGTAAGACACAGCATTCAACACTGTCACGAAAATTTGTTGAAGTGATGTCCGAATACAACGCCACACAATCCGACTACCGTGAGCGATGCAAAGGCCGCATCCAGCGACAGCTGGAAATCACTGGCAGGACCACAACCAGTGAAGAGCTGGAGGACATGCTGGAGAGTGGAAATCCAGCTATTTTCTCCTCAGGGATAATTATGGATTCCAATATTACCAAGCAGGCTCTAAATGAAATCGAGACGCGGCACAGTGAAATCATCAAGCTAGAGAACAGCATCCGCGAGCTGCATGATATGTTCATGGACATGGCTATGCTTGTAGAGAGTCAGGGTGAAATGATCGACCGCATAGAGTATAATGTGGAACACTCCGTGGATTATGTGGAAAGAGCAGTGTCCGACACCAAGAAGGCAGTCAAGTACCAGAGTAAAGCCAGAAGGAAGAAAATCATGATCATTATCTGCTGTGTGGTGCTGGGTATTGTCATTGCTTCAACATTTGGAGGGATTTTTGGATAAGGCAAGCGGAGCGGCACAGAATGCATGTTCTGGACATTGGAAGACATATGCAGCACACAGTGTGTGCCCTGTACAACGAGGCACTGGCAGTGGAAAAACAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001072191|syntaxin 1A (brain) [Xenopus (Silurana) tropicalis] MKDRTRELRAAKDSDEDDEVTVSLDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKAELEELMSDIKKTANKVRSKLKGIEQSIEQEEAMNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFSSGIIMDSNITKQALNEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGIVIASTFGGIFG

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.55681
Unigene EST Profile		EST Profile
GEO data			GEO
Images		2 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	STX1A
mouse		MGI	Stx1a	All(7) Targeted, knock Out(4) Targeted, other(1)
zebrafish

Publications
First:		Functional impact of syntaxin on gating of N-type and Q-type calcium channels. [Nature 1995]
Most recent:		Regulation of Neuronal M-Channel Gating in an Isoform-Specific Manner: Functional Interplay between Calmodulin and Syntaxin 1A. [J Neurosci 2011]
		View All Papers

Functional Ontologies
GO: Molecular:		protein transporter activity
Biological:		intracellular protein transport
Cellular Component:		membrane
EC:
KOG:		[U] SNARE protein Syntaxin 1 and related proteins

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Str.12098.1.S1_at
Affymetrix 2.0

Symbol legend[+]

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