Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (24) GO Terms (12) Nucleotides (182) Proteins (36) Interactants (661) Wiki
XB-GENEPAGE-977361
Gene Symbol: dvl3

Gene Name: dishevelled segment polarity protein 3

Synonyms: dishevelled3 , dsh3 ( Add synonyms , Nomenclature history )

Gene Function: wnt signal transduction

Protein Function :
Involved in the signal transduction pathway mediated by multiple Wnt genes. Required during ciliogenesis for the docking of basal bodies to the apical plasma membrane.

Interactants: Loading ...
Disease Ontology: autosomal dominant Robinow syndrome 1

OMIM Diseases: ROBINOW SYNDROME, AUTOSOMAL DOMINANT 1; DRS1 [+]

1/4
 
Xenbase Gene ID XB-GENE-977362 XB-GENE-977365 XB-GENE-17335212
Gene Symbol dvl3 dvl3.L dvl3.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 100144702
Entrez Gene: 444527
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine dvl3 dvl3.L dvl3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DVL3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Dvl3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR dvl3a ZFIN Ensembl
chicken
GEISHA DVL2 Ensembl
fruit fly
worm
WORMBASE
Publications
First Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis., Proc Natl Acad Sci U S A 2005  
Most Recent Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1., Nat Commun 2019                    
All View All Papers 7 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 7 terms 0 term
PANTHER dvl3
KEGG Pathways K02353 K02353
KOG [R] Dishevelled 3 and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon
Antibody Dvl2 Ab1 , Dvl3 Ab1 , dvl3 Ab3 Dvl2 Ab1 , Dvl3 Ab1 , dvl3 Ab3 dvl3 Ab3
Morpholino dvl3 MO1 , dvl3 MO2 , dvl3 MO3 dvl3 MO1 , dvl3 MO2 , dvl3 MO3 dvl3 MO1 , dvl3 MO2 , dvl3 MO3
Affymetrix 1.0 Str.29977.1.A1_x_at [+] Xl.24099.1.A1_at
Affymetrix 2.0 Xl2.24099.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.1


Major funding for Xenbase is provided by grant P41 HD064556