Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (99) GO Terms (33) Nucleotides (275) Proteins (47) Interactants (536) Wiki
XB-GENEPAGE-978998
Gene Symbol:
kif11

Gene Name:
kinesin family member 11

Synonyms:
eg5 , hksp , knsl1 , trip5 , cos2 , costal2 , kif11-a , kif11-b ( Add synonyms , Nomenclature history )

Gene Function:
Kinesin-like protein

Protein Function :
Plus end-directed motor protein required for establishing a bipolar spindle (PubMed:15583027). Associates with both interphase and spindle microtubules (PubMed:15583027). May be involved in nuclear div...[+]


InterPro :
MYCBPAP , ATPase P-typ TM dom sf , HAD-like sf , P-type ATPase IIC [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
microcephaly with or without chorioretinopathy, lymphedema, or mental retardation

OMIM:
MICROCEPHALY WITH OR WITHOUT CHORIORETINOPATHY, LYMPHEDEMA, OR MENTAL RETARDATIO

External Links:
 
Xenbase Gene ID XB-GENE-978999 XB-GENE-979004 XB-GENE-6252175
Gene Symbol kif11 kif11.L kif11.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 548870
379112
397908
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot Uniprot GO RefSeq RefSeq Swiss-Prot
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine kif11 kif11.L kif11.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KIF11 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kif11 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kif11 Ensembl
zebrafish
ZFIN, AGR kif11 ZFIN Ensembl
chicken
GEISHA KIF11 Ensembl
fruit fly
worm
Publications
First Cloning by differential screening of a Xenopus cDNA that encodes a kinesin-related protein., Mol Cell Biol 1991  
Most Recent Translational Control of Xenopus Oocyte Meiosis: Toward the Genomic Era., Cells 2020              
All View All Papers 3 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 32 terms 9 terms 11 terms
PANTHER kif11
KEGG Pathways K10398 K10398 K10398
KOG [Z] Kinesin-like protein (alt_id KOG:0243)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks kif11
Antibodies Kinesin Ab5 Kinesin Ab4 , Kinesin Ab5 Kinesin Ab4 , Kinesin Ab5
Morpholinos kif11 MO1 , kif11 MO2 kif11 MO1 , kif11 MO2 kif11 MO1 , kif11 MO2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556