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Summary Expression Gene Literature (77) GO Terms (7) Nucleotides (701) Proteins (41) Interactants (474) Wiki
XB-GENEPAGE- 979093

Gene Symbol: rcc1

Gene Name: regulator of chromosome condensation 1

Synonyms: xrcc1 , RanGEF , chc1 , rcc1-a , rcc1-b
Add Xenopus synonyms , Nomenclature history


Gene Function: Uncharacterized conserved protein, contains RCC1 domain

Protein Function :
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the g...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
  
 

Xenbase Gene ID XB-GENE-979094 XB-GENE-6252622 XB-GENE-979099
Gene Symbol rcc1 rcc1.L rcc1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.6824 [+] Xl.29555 Xl.61063 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 2 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine rcc1 rcc1.L rcc1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards RCC1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Rcc1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR rcc1 ZFIN Ensembl
chicken
GEISHA RCC1 Ensembl
fruit fly
FLYBASE Rcc1 Ensembl
worm
WORMBASE
Publications
First: Cloning of Xenopus RCC1 cDNA, a homolog of the human RCC1 gene: complementation of tsBN2 mutation and identification of the product. [J Biochem 1990]
Most recent: Subcellular scaling: does size matter for cell division? [Curr Opin Cell Biol 2018]
View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 7 terms 0 term
PANTHER rcc1
KEGG Pathways K11493 K11493 K11493
KOG [S] Uncharacterized conserved protein, contains RCC1 domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino rcc1 MO1 rcc1 MO1 rcc1 MO1
ORF rcc1.L ORF1 rcc1.S ORF1 , rcc1.S ORF2
Affymetrix 1.0 Str.6824.1.S1_at [+] Xl.208.1.S1_at Xl.16490.2.A1_at [+]
Affymetrix 2.0 Xl2.29555.1.S1_at Xl2.25839.1.S1_x_at [+]

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556