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Summary Expression Gene Literature (25) GO Terms (3) Nucleotides (28) Proteins (15) Interactants (151) Wiki
XB-GENEPAGE- 980660

Gene Symbol: lep

Gene Name: leptin

Synonyms: obesity homolog , leptin , xlep
Add Xenopus synonyms , Nomenclature history


Gene Function:

Protein Function :
Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in t...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
   LEPTIN DEFICIENCY OR DYSFUNCTION; LEPD
 

Xenbase Gene ID XB-GENE-980661 XB-GENE-17342421 XB-GENE-980662
Gene Symbol lep lep.L lep.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.86681 Xl.54052
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 2 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine lep lep.L lep.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LEP OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Lep MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR lepb lepa ZFIN Ensembl
chicken
GEISHA LEP Ensembl
fruit fly
FLYBASE lep Ensembl
worm
WORMBASE
Publications
First: [Use of colloidal gold in ultrastructural cytochemistry]. [Cesk Patol 1985]
Most recent: JAK-STAT pathway activation in response to spinal cord injury in regenerative and non-regenerative stages of Xenopus laevis. [Regeneration (Oxf) 2017]
View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 3 terms 3 terms
PANTHER lep
KEGG Pathways K05424 K05424
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Lep Ab1 Lep Ab1 Lep Ab1
Affymetrix 1.0 StrJgi.211.1.S1_at
Affymetrix 2.0 Xl2.54052.1.S1_at

Symbol legend[+]
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