Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (45) GO Terms (0) Nucleotides (20) Proteins (11) Interactants (74) Wiki
XB-GENEPAGE- 981143

Gene Symbol: slc6a4

Gene Name: solute carrier family 6 (neurotransmitter transporter), member 4

Synonyms: htt , 5htt , ocd1 , sert , 5-htt , 5-httlpr
Add Xenopus synonyms , Nomenclature history


Gene Function: Sodium-neurotransmitter symporter

Protein Function:


Interactants: YYY

OMIM Disease Associations: OBSESSIVE-COMPULSIVE DISORDER; OCD [+]
 
Xenbase Gene ID XB-GENE-981144 XB-GENE-17344932 XB-GENE-17344933
Gene Symbol slc6a4 slc6a4.L slc6a4.S
Chromosome scaffold_63 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide
Protein NCBI Protein
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine slc6a4 slc6a4.L slc6a4.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SLC6A4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Slc6a4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN slc6a4b slc6a4a ZFIN Ensembl
chicken
GEISHA SLC6A4 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel. [J Neurosci 1997]
Most recent: The external gate of the human and Drosophila serotonin transporters requires a basic/acidic amino acid pair for 3,4-methylenedioxymethamphetamine (MDMA) translocation and the induction of substrate efflux. [Biochem Pharmacol 2016]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 0 term
EC
PANTHER slc6a4
KEGG Pathways
KOG [T] Sodium-neurotransmitter symporter
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Affymetrix 1.0 StrEns.581.1.S1_a_at
Affymetrix 2.0

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556