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Summary Expression Gene Literature (8) GO Terms (24) Nucleotides (134) Proteins (49) Interactants (186) Wiki
XB-GENEPAGE-982495
Gene Symbol:
plcg1

Gene Name:
phospholipase C gamma 1

Synonyms:
PLC gamma 1 , plc1 , nckap3 , plc-ii , plc148 , plcgamma1 ( Add synonyms , Nomenclature history )

Gene Function:
Phospholipase C

Protein Function :
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.


InterPro :
EF hand dom , PLC-gamma N-SH2 , SH2 dom sf , PLC-gamma C-SH2 [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-982496 XB-GENE-982499 XB-GENE-17342909
Gene Symbol plcg1 plcg1.L plcg1.S
Chromosome Chr10 chr9_10L Scaffold94
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100496674
398359
398360
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine plcg1 plcg1.L plcg1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PLCG1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Plcg1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Plcg1 Ensembl
zebrafish
ZFIN, AGR plcg1 ZFIN Ensembl
chicken
GEISHA PLCG1 Ensembl
fruit fly
worm
Publications
First Phosphorylation of phospholipase C gamma 1 and its association with the FGF receptor is developmentally regulated and occurs during mesoderm induction in Xenopus laevis., Dev Biol 1994  
Most Recent AKT signaling displays multifaceted functions in neural crest development., Dev Biol 2018  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 24 terms 6 terms 6 terms
PANTHER plcg1
KEGG Pathways K01116 K01116 K05859 [+]
KOG [I] Phospholipase C
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks plcg1
Morpholinos (on-target & off-target) plcg1 MO1
ORFs plcg1.L ORF1 plcg1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info