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Summary Expression Gene Literature (19) GO Terms (91) Nucleotides (115) Proteins (33) Interactants (113) Wiki
XB-GENEPAGE-982560
Gene Symbol:
blm

Gene Name:
Bloom syndrome RecQ like helicase

Synonyms:
xBLM , Bloom syndrome ( Add synonyms , Nomenclature history )

Gene Function:
ATP-dependent DNA helicase

Protein Function :
ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction. Participates in DNA replication and repair (PubMed:11040210). Involved in 5'-end resection of DNA during do...[+]



Interactants:
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Diseases: 


Disease Ontology:
Bloom syndrome

OMIM:
BLOOM SYNDROME; BLM

External Links:
 
Xenbase Gene ID XB-GENE-982561 XB-GENE-17332662 XB-GENE-982565
Gene Symbol blm blm.L blm.S
Chromosome Chr03 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100124311
108711520
373628
mRNA RefSeq NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine blm blm.L blm.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BLM OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Blm MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Blm Ensembl
zebrafish
ZFIN, AGR blm ZFIN Ensembl
chicken
GEISHA BLM Ensembl
fruit fly
FLYBASE Blm Ensembl
worm
Publications
First DNA ligase III is the major high molecular weight DNA joining activity in SV40-transformed human fibroblasts: normal levels of DNA ligase III activity in Bloom syndrome cells., Nucleic Acids Res 1993  
Most Recent RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR., Cell Cycle 2019                
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 88 terms 7 terms 22 terms
PANTHER blm
KEGG Pathways K10901 K10901 K10901
KOG [L] ATP-dependent DNA helicase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks blm
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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