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Summary Expression Gene Literature (3) GO Terms (5) Nucleotides (118) Proteins (36) Interactants (649) Wiki
XB-GENEPAGE- 983791

Gene Symbol: dnal1

Gene Name: dynein, axonemal, light chain 1

Synonyms:
Add Xenopus synonyms , Nomenclature history

Gene Function: Protein phosphatase 1, regulatory subunit, and related proteins

Protein Function :
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency. Component of the outer arm dynein (ODA). May be involved in a mechanosensory fee...[+]


Interactants: Loading ...

Disease Ontology:
   PRIMARY CILIARY DYSKINESIA 16

OMIM Diseases:
   CILIARY DYSKINESIA, PRIMARY, 16; CILD16
1/2
 

Xenbase Gene ID XB-GENE-983792 XB-GENE-983797 XB-GENE-17346447
Gene Symbol dnal1 dnal1.L dnal1.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.26524 Xl.49781
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 6 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine dnal1 dnal1.L dnal1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas030a23      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DNAL1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Dnal1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR dnal1 ZFIN Ensembl
chicken
GEISHA DNAL1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides. [PLoS Genet 2006]
Most recent: Coordinated genomic control of ciliogenesis and cell movement by RFX2. [Elife 2014]
View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 5 terms 0 term
PANTHER dnal1
KEGG Pathways K10411 K10411
KOG [T] Protein phosphatase 1, regulatory subunit, and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino dnal1 MO1 , dnal1 MO2 dnal1 MO1 , dnal1 MO2 dnal1 MO1 , dnal1 MO2
ORF dnal1.L ORF1
Affymetrix 1.0 Str.26524.1.S1_at
Affymetrix 2.0 Xl2.49781.1.S1_at

Symbol legend[+]
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.9.1
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556