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Summary Expression Gene Literature (73) GO Terms (16) Nucleotides (609) Proteins (31) Interactants (475) Wiki
XB-GENEPAGE-984046
Gene Symbol:
cltc

Gene Name:
clathrin, heavy chain (Hc)

Synonyms:
Clathrin ( Add synonyms , Nomenclature history )

Gene Function:
Vesicle coat protein clathrin, heavy chain

Protein Function :
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.


InterPro :
Clathrin heavy chain , Clathrin H-chain N , TPR-like helical dom sf , Clathrin H-chain linker core [+]

Interactants:
Loading ...

Diseases: 


OMIM:
MENTAL RETARDATION, AUTOSOMAL DOMINANT 56; MRD56

External Links:
 
Xenbase Gene ID XB-GENE-984047 XB-GENE-984052 XB-GENE-17335555
Gene Symbol cltc cltc.L cltc.S
Chromosome Chr02 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 496448
444287
108709605
mRNA RefSeq RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cltc cltc.L cltc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CLTC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cltc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cltc Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR cltca cltcb ZFIN Ensembl
chicken
GEISHA CLTC Ensembl
fruit fly
worm
Publications
First Immunological identification and localization of clathrin and coated vesicles in cultured cells and in tissues., Exp Cell Res 1981  
Most Recent Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation., Sci Rep 2019                            
All View All Papers 7 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 8 terms 7 terms
PANTHER cltc
KEGG Pathways K04646 K04646 K04646
KOG [U] Vesicle coat protein clathrin, heavy chain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cltc
Antibodies cltc Ab1 , cltc Ab2 cltc Ab1 , cltc Ab2 cltc Ab1 , cltc Ab2
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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