Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (29) GO Terms (11) Nucleotides (24) Proteins (13) Interactants (56) Wiki
XB-GENEPAGE- 984749

Gene Symbol: htr1a

Gene Name: 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Synonyms: 5ht1a , 5-ht1a , adrbrl1 , adrb2rl1
Add Xenopus synonyms , Nomenclature history


Gene Function: Muscarinic acetylcholine receptor

Protein Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers sig...[+]


Interactants: YYY

OMIM Disease Associations: PERIODIC FEVER, MENSTRUAL CYCLE-DEPENDENT
 
Xenbase Gene ID XB-GENE-984750 XB-GENE-984751 XB-GENE-17332668
Gene Symbol htr1a htr1a.L htr1a.S
Chromosome Chr01 chr1L Scaffold53
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Xl.1104
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 2 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine htr1a htr1a.L htr1a.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HTR1A OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Htr1a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN htr1ab htr1aa ZFIN Ensembl
chicken
GEISHA HTR1A Ensembl
fruit fly
worm
WORMBASE
Publications
First: The orphan receptor cDNA RDC4 encodes a 5-HT1D serotonin receptor. [Biochem Biophys Res Commun 1991]
Most recent: SAR-studies on the importance of aromatic ring topologies in search for selective 5-HT(7) receptor ligands among phenylpiperazine hydantoin derivatives. [Eur J Med Chem 2014]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 11 terms 0 term
EC
PANTHER htr1a
KEGG Pathways K04153
KOG [T] Muscarinic acetylcholine receptor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Affymetrix 1.0 StrEns.2660.1.S1_at Xl.1104.1.S1_at
Affymetrix 2.0 Xl2.1104.1.S1_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556