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Summary Expression Gene Literature (3) GO Terms (16) Nucleotides (105) Proteins (44) Interactants (330) Wiki
XB-GENEPAGE-985510
Gene Symbol:
srd5a3

Gene Name:
steroid 5 alpha-reductase 3

Synonyms:
SRD5alpha3 ( Add synonyms , Nomenclature history )

Gene Function:
Predicted steroid reductase

Protein Function :
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosacch...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
congenital disorder of glycosylation type I [+]

OMIM:
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iq; CDG1Q [+]

External Links:
 
Xenbase Gene ID XB-GENE-985511 XB-GENE-17336642 XB-GENE-985517
Gene Symbol srd5a3 srd5a3.L srd5a3.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 779994
108698470
379123
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot NCBI Protein RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine srd5a3 srd5a3.L srd5a3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SRD5A3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Srd5a3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Srd5a3 Ensembl
zebrafish
ZFIN, AGR srd5a3 ZFIN Ensembl
chicken
GEISHA SRD5A3 Ensembl
fruit fly
worm
Publications
First Steroid 5-reductases are functional during early frog development and are regulated via DNA methylation., Mech Dev 2016            
Most Recent Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis., Gen Comp Endocrinol 2018              
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 0 term 10 terms
PANTHER srd5a3
KEGG Pathways K12345 K12345
KOG [I] Predicted steroid reductase
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks srd5a3
ORFs srd5a3 ORF1 srd5a3.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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