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Summary Expression Gene Literature (3) GO Terms (14) Nucleotides (88) Proteins (36) Interactants (330) Wiki
XB-GENEPAGE-985510
Gene Symbol: srd5a3

Gene Name: steroid 5 alpha-reductase 3

Synonyms: SRD5alpha3 ( Add synonyms , Nomenclature history )

Gene Function: Predicted steroid reductase

Protein Function :
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosacch...[+]


Interactants: Loading ...
Disease Ontology: congenital disorder of glycosylation type I [+]

OMIM Diseases: CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iq; CDG1Q [+]

 
Xenbase Gene ID XB-GENE-985511 XB-GENE-17336642 XB-GENE-985517
Gene Symbol srd5a3 srd5a3.L srd5a3.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.1
CDS Gene model
Entrez Gene: 779994
Entrez Gene: 108698470
Entrez Gene: 379123
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq TrEMBL Swiss-Prot NCBI Protein RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine srd5a3 srd5a3.L srd5a3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SRD5A3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Srd5a3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR srd5a3 ZFIN Ensembl
chicken
GEISHA SRD5A3 Ensembl
fruit fly
worm
WORMBASE
Publications
First Steroid 5-reductases are functional during early frog development and are regulated via DNA methylation., Mech Dev 2016            
Most Recent Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis., Gen Comp Endocrinol 2018              
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 0 term 10 terms
PANTHER srd5a3
KEGG Pathways K12345 K12345
KOG [I] Predicted steroid reductase
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon Horizon
ORF srd5a3 ORF1 srd5a3.S ORF1
Affymetrix 1.0 Str.24988.1.S1_at Xl.15326.1.S1_at
Affymetrix 2.0 Xl2.15326.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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